Thank you all for the information and F estimator write-up.
With regards
Karthik
On 13-03-2017 03:56 AM, Phil Evans wrote:
Sorry Ian, I was attributing this to Kevin
apologies
Phil
On 12 Mar 2017, at 21:56, Ian Tickle wrote:
Eleanor,
Phil is right about the bias of the weighted mean,
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Hi
I am comparing some protein complex with PISA analysis. Can someone make a
note what is difference between interface area and buried surface area. I
think buried surface area also include the interface area + the area
encloses with in the protein. Does it make sense to mentioned the interface
ar
Thanks all for the help!
Definitely, using: Extensions -> Modelling -> Replace Residue ... -> CSD ->
Mutate was the easiest way to solve the problem of adding the sulfinic
cysteine!
Thanks
Renato
*Renato Mateus Domingos*
*PhD student at Departamento de Genética e Biologia Evolutiva*
*Universidad
Hi Eleanor
I reran my simulation including your method. Let's just look at the two
extreme cases in my original table: sd(F+) = 10, sd(F-) = 1 (5th row) and
sd(F+) = 1000, sd(F-) = 100 (last row: the case where my method performs
worst but still better than the others!). I used the same 'true' v
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Eleanor
I notice that you are calculating a weighted mean using 1/sd(I) as the
weight whereas in least squares one would of course normally use
variance-weighting, i.e. 1/sd(I)^2. I assume this is intentional and is a
way to reduce the bias effect of weighting, so that the resulting bias of
the m
