[ccp4bb] Postdoc in evolutionary biochemistry, Thornton Lab, University of Chicago

2019-01-04 Thread Joseph W Thornton
Postdoc position in evolutionary biochemistry, Thornton Lab, University of Chicago We have an opening for a postdoc in protein evolution and functional molecular evolution. The lab’s goal is to characterize the evolutionary, genetic and biochemical mechanisms by which biological molecules acqu

Re: [ccp4bb] Refinement with native and anomalous data

2019-01-04 Thread Piotr Wilk
>My advice is to simply cycle back-and-forth between the two data sets. Refine against your high-resolution data until that converges, then simply >switch to the other mtz file and use F+ F-, along with "anomalous wavelength" and probably "refine orefine no", unless you want to refine the >occupan

Re: [ccp4bb] Refinement with native and anomalous data

2019-01-04 Thread James Holton
My advice is to simply cycle back-and-forth between the two data sets.  Refine against your high-resolution data until that converges, then simply switch to the other mtz file and use F+ F-, along with "anomalous wavelength" and probably "refine orefine no", unless you want to refine the occupa

[ccp4bb] Cryo EM director position at NYU

2019-01-04 Thread Gira Bhabha
Hi All: NYU, located in New York City, is recruiting a cryo EM director (research track faculty position), and we would love to hear from you. Details below. Please don’t hesitate to email me directly with any questions, and please apply if interested! Best, Gira ———

Re: [ccp4bb] Refinement with native and anomalous data

2019-01-04 Thread Steiner, Roberto
Dear Piotrek You can find some info on the use of prior phase information in refinement with Refmac in Acta Crystallogr D Biol Crystallogr. 2011 Apr;67(Pt 4):355-67. doi: 10.1107/S0907444911001314. Epub 2011 Mar 18. REFMAC5 for the refi

Re: [ccp4bb] Refinement with native and anomalous data

2019-01-04 Thread Piotr Wilk
Dear Eleanor, I have used the ACORN previously for structure solution but I will have to read more about its functionality in structure refinement. I have run two Refmac jobs using either native or anomalous data with otherwise default parameters resulting in R/Rfree of 0.2013/0.2458 and 0.1862/0.

[ccp4bb] Postdoctoral Position Structural Biology and Vaccine, Seattle, WA

2019-01-04 Thread Pancera, Marie
Hello, See Postdoc Position in Structural Biology for Vaccine Design at Fred Hutchinson Cancer Research Center, Seattle, WA. Happy New Year, Marie https://careers-fhcrc.icims.com/jobs/12660/

[ccp4bb] PhD position

2019-01-04 Thread Aravindan Ilangovan
Dear all Please share with anyone who might be interested. I have a PhD position to start in my research group in October 2019 at Queen Mary University of London. https://www.findaphd.com/phds/project/structural-studies-of-the-molecular-systems-that-maintain-and-spread-antibiotic-resistance-i