> On 5 Jun 2019, at 20:40, Paul Emsley wrote:
>
> Ctrl-S will do Quick save as, saving your state files and any unsaved models
> with file-name increments. That should put your mind to rest about unsaved
> changes. Also, investigate the coot-backup directory - coot should be saving
> models
On 05/06/2019 20:31, Jonathan Cooper wrote:
> For the past few weeks I have noticed that when you start Coot from
> the i2 gui it works fine for up to an hour or so but then its hangs
> completely and any unsaved changes go missing. It seems more stable if
> I start it outside the i2 gui. Is this
For the past few weeks I have noticed that when you start Coot from the i2 gui
it works fine for up to an hour or so but then its hangs completely and any
unsaved changes go missing. It seems more stable if I start it outside the i2
gui. Is this just me or my linux box?
Dear all,
A PhD position is available in my group at the Institute for Structural Biology
in Grenoble.
We are looking for a highly motivated student to work on a chromatin-binding
complex as a potential target for developing new antifungal drugs. The project
involves protein expression and
On 06/05/2019 10:07 AM, Randy Read wrote:
Dear Ian,
I think the missing ingredient in your argument is an assumption that may be
implicit in what others have written: if you have NCS in your crystal, you
should be restraining that NCS in your model. If you do that, then the
NCS-related
Dear colleagues
I would like to invite you to an interesting event focusing on XFEL and Cryo-EM
science. we have an amazing line-up of speakers. Also Switzerland is always
worth a visit!
I am excited to announce the final agenda for the International Symposium on
Structure Biology for Drug
Dear Ian,
I think the missing ingredient in your argument is an assumption that may be
implicit in what others have written: if you have NCS in your crystal, you
should be restraining that NCS in your model. If you do that, then the
NCS-related Fcalcs will be similar (especially in the
Just a reminder that the deadline for the summer school (14 June) is fast
approaching.
This year the University of York will be hosting the CCP4/BCA Protein
Crystallography Summer School, generously supported by CCP4, BCA, Alpha
Biotech, Bruker, Hampton Research, MiTeGen, Molecular Dimensions
Hi Jon
Sorry I didn't intend for my response to be interpreted as saying that
anyone has suggested directly that the measurement errors of NCS-related
reflection amplitudes are correlated. In fact the opposite is almost
certainly true since the only obvious way in practice that errors in Fobs
Dear Jonathan,
if you could make changes to your model parameters in the PDB file such that
the intensity of exactly one reflection changes, and all others stay the same,
in that case, you could say your free R set was unbiased from the model. I
have read somewhere, that intensities were
Dear all,
registration for the 27th Protein Structure Determination in Industry (PSDI)
meeting, 3-5 November 2019, is now open:
https://psdi2019.org/
The meeting will be held at the Wellcome Genome Campus, Hinxton,
Cambridgeshire, UK. Workshops will take place on Sunday the 3rd of November,
Dear colleagues,
We are seeking an excellent and highly motivated postdoctoral candidate to lead
a project combining biochemistry, SPA cryoEM and crystallography to study
protein-DNA complexes that allow the insertion of large DNA segments into a
genome. The position is funded through an NNF
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