Dear all,
Instruct-ERIC invites applications for glycan analysis, made available through its partner laboratory at the Institute of Chemistry at the Slovak Academy of Sciences (SAS). Successful proposals submitted before 30 September will receive funding to cover the cost of instrument access. Glycosylation is an essential post-translational modification of proteins that affects their function, folding, biological activity and interactions. As such, knowledge of glycosylation is crucial for the development of biopharmacological products and recombinant proteins expressed by non-native hosts. The Institute of Chemistry (SAS) offers expertise in analysing the structure, conformation, and dynamics of mono-, oligo- and poly-saccharides, their derivatives and glycoconjugates, as well as in weak intermolecular interactions between proteins and carbohydrate molecules. All technology is available remotely, so that users will be able to post their samples to the laboratory, without the need for travel. A full analytical report will be provided, tailored to the individual requirements for each sample. What technology is available? High-resolution NMR (1D, 2D), mass spectrometry (including determination of the intact glycoprotein mass, N-glycan profiling and mapping protein N-glycosylation sites), infrared and Raman spectroscopy, surface plasmon resonance, atomic force microscopy, differential scanning calorimetry and RTG diffractometry. More details. (www.chem.sk/activities/analytics/<http://www.chem.sk/activities/analytics/>). The Institute also provides expertise in the theoretical analysis of carbohydrate structures by quantum-chemical approaches, such as density functional methods. Who can apply? Pre- and post-doctoral researchers based in Instruct-ERIC and Instruct-ULTRA participating countries: Belgium, Czech Republic, Denmark, Finland, France, Germany, Greece, Israel, Italy, Latvia, Lithuania, Netherlands, Portugal, Slovakia, Spain, Sweden, UK, as well as all EMBL researchers. When can I apply? We advise that applicants apply as soon as possible. The first approvals will be made on 30 August 2020, and the second on 30 September 2020. Samples must be received within one month of award, and all analysis will be completed by 30 November 2020. How do I apply? Once you have registered for an ARIA account (https://instruct-eric.eu/register/?t=instructeric), visit the Open Call page (https://instruct-eric.eu/submit-call/glycan-analysis-) to submit a short research proposal. All proposals will be subject to light touch peer review, and awards made based on the quality of the science. Funding will be available to cover instrument access. Find out more For more information visit our Open Call page (https://instruct-eric.eu/submit-call/glycan-analysis-). Best wishes, Instruct-ERIC Hub Marysa Chapman Project Assistant [instructlogo] Instruct-ERIC, Oxford House, Parkway Court, John Smith Drive, Oxford, OX4 2JY, UK. Telephone: +44 (0) 1865 981492 Website: instruct-eric.eu<https://instruct-eric.eu> Twitter: @instructhub<https://twitter.com/instructhub> Dr Claudia Alén Amaro Senior Project Manager [instructlogo] Instruct-ERIC, Oxford House, Parkway Court, John Smith Drive, Oxford, OX4 2JY, UK. Telephone: +44 (0) 1865 987629 +44 (0) 7494060412 Website: instruct-eric.eu<https://instruct-eric.eu> Twitter: @instructhub<https://twitter.com/instructhub> ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
