[ccp4bb] Postdoctoral position available at the Institute of Cancer Research, London UK

2021-01-26 Thread Rob Van Montfort
The Institute of Cancer Research (ICR), London, is one of the world’s most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. Under the leadership of our Chief Executive, Professor Paul Workman FMedSci, the ICR is ranked as the UK’s

[ccp4bb] AbbVie industrial postdoc position available

2021-01-26 Thread Nocek, Boguslaw P
Hello Everyone, A postdoctoral position is available immediately in the Cystic Fibrosis Group led by Dr. Ashvani Singh at AbbVie Inc, in Illinois, USA. Successful candidate will work with a cross-functional team of researchers to Investigate the Structure-Function Relationship of CFTR Using CF

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2021-01-26 Thread Sridhar Prasad
*G. Sridhar Prasad, PhD* *Chief Scientific Officer* *Plex Pharmaceuticals & Collidion Inc.* *6330 Nancy Ridge Drive, S105**San Diego, CA 92121* *Ph: 858-587-8800 (o)**858-733-0858 (M)* *spra...@plexpharma.com * *www.plexpharma.com * *www.collidion.com

Re: [ccp4bb] Help for Twin Refinement in Refmac5 / CCP4i2

2021-01-26 Thread Eleanor Dodson
I fell into the same trap this week. Apparently if in the first screen you tick the box Crystal is twinned” the interface resets the input data to FMEAN (or IMEAN if you have asked to use intensitirs) and you don’t need to say TWIN . Semi logical I guess but easy to miss. Eleanor On Tue, 26 Jan 20

[ccp4bb] Imaging system

2021-01-26 Thread Linnert, Dr. Miriam
Dear all, We are looking to purchase a new imaging & plate storage system for protein crystallization. I would be interested to know what other people use and what their personal opinion (experience) of the available options is. Please feel free to contact me directly. Thanks in advance, Miria

[ccp4bb] Postdoctoral position at ICTER in Warsaw, Poland

2021-01-26 Thread Humberto Fernandes
Dear all This is a final reminder for this post. The closing date is the 31st of January. In the Integrated Structural Biology laboratory at The International Center for Translational Eye Research (ICTER) in Warsaw, Poland, one postdoctoral position is available for highly motivated bi

Re: [ccp4bb] Characterising potential drug-binding pockets

2021-01-26 Thread Barone, Matthias
Hi Sergei I assume that you used the term "drug-like fragments" because you would like to sort out candidates? The paper referenced by Bernhard is a good way to go, but it reflects exactly the problem of PPIs, namely that proteins with well defined binding pockets for substrates (such as kinase