[ccp4bb] A question about ShelxC, D and E

Dear all: When using Shelx, there are two input file formats(scalepack or mtz) to select. If scalepack format input file is selected, both native data and HA data is in need. But if mtz format input file is selected, only HA data is in need. Why this difference exist ? Is there a dif

[ccp4bb] viral protein BLAST

Dear All, Sorry to be disturbing you with my new inquiry. I always got great and trustworthy results using FUGUE (Protein homology recognition using environment-specific amino acid substitution tables:  https://mizuguchilab.org/fugue/prfsearch.html)  I use an amino acid sequence of a viral protei

Re: [ccp4bb] viral protein BLAST

PSI-BLAST (position specific iterative BLAST I think it stands for) and other BLAST variants may help - there are quite a few on NCBI now. There are also some other nice tools such as HHPred at https://toolkit.tuebingen.mpg.de/. Maybe HMMer could be a good option too. I’m not sure if any of th

Re: [ccp4bb] A question about ShelxC, D and E

Hello, it's a while since I ran Shelx and I imagine that you are running it through the i2 GUI, which isn't something I've tried yet. Unless it's changed a lot recently, shelx itself accepts the reflection data as h, k, l, F and sigma(F) (HKLF 3) or h, k, l, I and sigma(I) (HKLF 4). Bit rusty on

[ccp4bb] University of Essex Research Fellowship

Dear all, We welcome high-calibre candidates to join the Protein Structure and Mechanism of Disease (PSMD) division at the University of Essex via external Fellowships from funding age