Re: [ccp4bb] Protein model size is much bigger than EM map

Hi Jie, the most obvious thing to do (and you might have tried that already) is to adjust the voxel size (in Å) and/or the contouring level of the map within Chimera. Both are normally associated with the EMDB entry of the map (under "map information”). Try to adjust these values in Chimera usi

[ccp4bb] Experimental design and response surface methods for crystal optimization

Dear all I recently came across the "experimental design" method for systematic optimization of multiparametric problems like macromolecular crystal growth. (The response surface concept has been introduced to protein crystallization by Carter et al. (e.g. Meth. Mol. Biol, vol. 363) and should t