Dear all, Thank you very much for help!
The problem was solved very easy (thanks Dominik A. Herbs). I just used another program for refinement (Refmac5 instead Phenix.refine) and this "noisy" density almost disappeared. http://www.4sync.com/photo/--e2gHrG/Density-Refmac5.html Thanks a lot for help again! Best regards, Pavel V. Natashin PhD student Photobiology Laboratory Institute of Biophysics Russian Academy of Sciences Siberian Branch Krasnoyarsk 660036, Russia National Laboratory of Biomacromolecules Institute of Biophysics Chinese Academy of Sciences Beijing 100101, China
