Dear all, The Yue Lab, recently relocated to Newcastle, is recruiting 3 postdoc positions offering exciting opportunities in different flavours of structural biology/drug discovery, interacting closely with clinicians, industry, and patient groups.
All are two-year positions in the first instance, UK/EU/non-EU/international applicants all welcome. Deadline: *Monday 13 December*. We aim to fill these positions by Q1 2022. https://jobs.ncl.ac.uk/job/Newcastle-Research-Associate/711931801/ (job ID: 11461) You will drive a structure-based drug discovery project in an academic setting, funded by LifeArc and Action Medical Research, working closely with medicinal chemists in Oxford and clinical scientists in UCL towards hit-to-lead inhibitor optimisation for a rare epileptic disorder. (Skills: crystallography, SPR, activity assays, CETSA; bit of cryo-EM) https://jobs.ncl.ac.uk/job/Newcastle-Research-Associate-in-Structure-Based-Drug-Design/711711601/ (job ID: 11462) You will run an academic-industrial collaboration with Bicycle Therapeutics, towards structural and biophysical characterisation of bicyclic peptides in complex with novel therapeutic targets in immune-metabolism/oncology. (Skills: different expression approaches, crystallography, SPR; bit of cryo-EM) https://jobs.ncl.ac.uk/job/Newcastle-Research-AssistantAssociate-in-AI-&-fragment-based-drug-discovery/743752301/ (job ID: 13927) You will lead an early-stage discovery project funded by a patient foundation, towards small molecule therapy for Friedreich’s ataxia targeting a multi-protein complex. You will work closely with an AI company in hit finding, and run validation studies to guide compound design through machine learning (Skills: ITC, SPR, cryo-EM & x-ray, activity assays). You can find out more about our group here: https://www.staff.ncl.ac.uk/yuelab/ Any informal enquiries you can contact: wyatt....@newcastle.ac.uk *Wyatt Yue* Professor of Structural Biology Biosciences Institute Faculty of Medical Sciences Newcastle University NE2 4HH Group: www.staff.ncl.ac.uk/yuelab/ Profile: wyattyue.github.io ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/