Posted on behalf of Domainex.



Begin forwarded message:

From: Stefanie Reich <s.re...@domainex.co.uk<mailto:s.re...@domainex.co.uk>>
Date: 31. May 2019 at 17:04:20 CEST
To: "ccp4bb@jiscmail.ac.uk<mailto:ccp4bb@jiscmail.ac.uk>" 
<ccp4bb@jiscmail.ac.uk<mailto:ccp4bb@jiscmail.ac.uk>>
Subject: Domainex is hiring a Structural Biologist


https://www.domainex.co.uk/about-us/recruitment#3

  *



Domainex has a full-time permanent vacancy in our Protein Science Team, which 
offers our clients a comprehensive range of services including molecular 
biology, protein production for assays and structural biology, and structural 
analysis of proteins by X-ray crystallography.  Our unique, patented, 
Combinatorial Domain Hunting technology allows us to make and work with 
proteins that are otherwise refractory to recombinant expression.

All applicants must be able to solve X-ray crystal structures independently and 
have a good working knowledge of the current software packages employed in 
protein crystallography (esp. XDS, CCP4, coot). They should be able to 
demonstrate postdoctoral level experience of solving structures of 
protein-ligand complexes over a range of target classes in a drug discovery 
environment, experience in the use of biophysical techniques would be a 
significant plus. Candidates must also have expertise in molecular biology; 
recombinant protein expression and purification in E. coli, insect or mammalian 
cells; and substantial experience of using AKTA chromatography equipment (or 
similar) for protein purification to X-ray crystallography standard.

This role requires the ability to plan and implement experimental programmes, 
to solve any problems that arise, and to work effectively within project teams 
to deliver high-quality results to our clients. Laboratory work is a major 
element of this varied and challenging role.  Essential attributes include 
diligent reporting of results, data interpretation, and an ability to make 
recommendations for further studies. It will also be necessary to communicate 
your results effectively to our clients.



Job requirements:

PhD with track-record of relevant and proven experience, i.e. publications and 
PDB depositions.

Independence and team working; flexibility to take on different projects; 
ability to make a meaningful impact on clients.

Ability to work on your own initiative, and to consistently deliver high 
quality results.

Creative thinking coupled to delivery of novel outcomes that leads to 
opportunities for inventorship or publications (papers/research articles).



To apply for this role, please send your CV and a covering letter, quoting 
reference PS0519, to 
recruitment2...@domainex.co.uk<mailto:recruitment2...@domainex.co.uk>.







Email confidentiality notice: This message is private and confidential. If you 
have received this message in error, please notify us and remove it from your 
system. Domainex Ltd is registered in England and Wales. Company No. 04336899. 
Registered office: Chesterford Research Park, Little Chesterford, Saffron 
Walden, Essex, CB10 1XL, UK.


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