Re: [ccp4bb] Off-topic: chemical modification on thiol groups

2009-01-28 Thread Hannes Uchtenhagen
86 Stockholm, Sweden CIM: +46-(0)8-585 896 88 MTC: +46-(0)8-524 86216 Mobile: +46-(0)7-36901461 - Original Message - From: Remy Loris Date: Wednesday, January 28, 2009 2:47 pm Subject: [ccp4bb] Off-topic: chemical modification on thiol groups To: CCP4BB@JISCMAIL.AC.UK > I am look

Re: [ccp4bb] Off-topic: chemical modification on thiol groups

2009-01-28 Thread Dima Klenchin
I am looking for a reagent (and vendor) that will irreversible put a raher bulky substituent on a free SH group and that does not react with free amines (or other potential reactive groups present on a protein surface). The connection with crystallography is that it is required for an experimen

[ccp4bb] Off-topic: chemical modification on thiol groups

2009-01-28 Thread Remy Loris
I am looking for a reagent (and vendor) that will irreversible put a raher bulky substituent on a free SH group and that does not react with free amines (or other potential reactive groups present on a protein surface). The connection with crystallography is that it is required for an experimen