Dear colleagues,

We are looking for a PhD candidate (m/f/d) and a Postdoctoral researcher 
(m/f/d) to strengthen our structural biology/biochemistry team at the 
Humboldt-Universität zu Berlin (HU).

Our research focuses on the biochemical principles how archaea and bacteria use 
carbon monoxide (CO) and carbon dioxide (CO2) as carbon and/or energy source. 
We use protein crystallography in combination with protein 
chemistry/spectroscopy and kinetics to study the structure, mechanism and 
assembly of the (multi)complex metalloenzymes at the heart of these molecular 
energy conversions.

Our laboratory has state-of-the-art facilities for protein production, 
biochemical characterisation, and protein crystallisation/x-ray 
crystallography. HU is a member of the Joint Berlin MX-Laboratory, enabling 
direct access to the local synchrotron facility (BESSY II, Berlin).

For more details see: 
https://www.biologie.hu-berlin.de/en/gruppenseiten-en/struktbio 
<https://www.biologie.hu-berlin.de/en/gruppenseiten-en/struktbio>

Postdoctoral position:
You should have a university degree and PhD in biochemistry, chemistry, 
biophysics or biology. Expertise in either x-ray crystallography, preparative 
(recombinant) protein production and/or functional characterisation is 
essential. Previous research experience should be documented through 
peer-reviewed publications (at least one as first author).
The focus of your contribution to the research projects will be on 
cofactor-dependent enzymatic reactions, protein crystallography and enzymology. 
You will contribute to the lectures by assisting in the design, organisation 
and supervision of lectures, seminars and practical courses. These tasks will 
allow you to acquire and train skills for further academic qualifications.

PhD position:
You should have a university degree in biochemistry, chemistry, biophysics or 
biology. Experience in biochemical, biophysical and structural biology methods, 
especially in the characterisation of enzymes is welcome.
You will work in the research project “Fe/S-double-cubane-cluster: a new 
cofactor in biology (DCCP)” within the priority program “Fe/S-clusters for 
life” (https://www.ironsulfurforlife.de <https://www.ironsulfurforlife.de/>). 
Your tasks are the purification and the biochemical and structural 
characterization of oxygen-sensitive metalloenzymes in order to elucidate the 
role of Fe/S-double cubane-clusters.

Both positions are funded for 3 years (German salary level E 13 TV-L HU for 
postdoctoral fellow, 0,65 E 13 TV-L for PhD fellow). Please submit your 
application (letter of application, CV and two references) preferentially 
electronically (a single PDF file not exceeding 10 MB) with a subject line 
“AN/300/19” for the postdoctoral position and “DR/187/19” for the PhD position. 
Deadline for application is 30.10.2019.

Email contact: holger.dob...@biologie.hu-berlin.de 
<mailto:holger.dob...@biologie.hu-berlin.de>

Holger Dobbek
Structural Biology/Biochemistry
Humboldt-Universität zu Berlin
Germany


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