*PhD position at the Institute for Structural Biology, Grenoble, France *

/Development of ultrastable fluorescent proteins for quantitative super resolution microscopy at cryogenic temperature./

The recruited student will work in the Pixel team: http://www.ibs.fr/research/research-groups/dynamics-and-kinetics-of-molecular-processes-group-m-weik/pixel/ He/she will investigate the structural photophysics of fluorescent proteins used as markers in super-resolution microscopy in conditions of cryogenic temperature. The ultimate goal will be to engineer a variant that efficiently photoactivates at such low temperature.

Candidates should have a strong background in biophysics and/or biochemistry. Preliminary experience in protein crystallography, molecular biology and/or advanced optical microscopy will be key advantages.

The project will start in September/October 2019 and is financed by the French “CEA” (“Thèse Phare”):

see http://www-instn.cea.fr/formations/formation-par-la-recherche/doctorat/liste-des-sujets-de-these/developpement-de-marqueurs-fluorescents-ultrastables-pour-la-cryo-microscopie-super-resolution,19-06.html

Applications are now open. Please send a CV, a motivation letter and 2 reference letters to Dominique Bourgeois (dominique.bourge...@ibs.fr <mailto:dominique.bourge...@ibs.fr>).


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Dominique BOURGEOIS

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Equipe PIXEL
Groupe DYNAMOP
Institut de Biologie Structurale J-P. Ebel
IBS
71 AVENUE DES MARTYRS
CS 10090
38044 GRENOBLE CEDEX 9
FRANCE
Tel: 33-(0)4 57 42 86 44 Fax: 33-(0)4 76 50 18 90
http://www.ibs.fr/research/research-groups/dynamics-and-kinetics-of-molecular/pixel/
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