Imperial College London

Department of Life Sciences 

Faculty of Natural Sciences

Research Associate

Salary: £32,100 - £35,620 per annum

We wish to recruit a Research Associate for up to 24 months in the first 
instance with possible extension to up to five years to work in the research 
group of Professor Paul Freemont and Professor Xiaodong Zhang 
(http://www.msf.bio.ic.ac.uk/index.php)  in the Centre for Structural Biology, 
Department of Life Sciences at the South Kensington Campus of Imperial College 
London. 

Our research group comprise research fellows, research associates and PhD 
students from a diverse range of background including molecular biology, 
biochemistry, X-ray crystallography, electron microscopy, physics and 
engineering. We employ a multi-disciplinary approach to study the structures 
and mechanisms of large macromolecular complexes.

Funded by a CRUK programme grant to Professor Paul Freemont and Professor 
Xiaodong Zhang, you will join a multi-disciplinary group to investigate the 
structure and mechanism of the AAA ATPase p97. p97 is a versatile participant 
of the ubiquitin proteasome system, interacting with a larger network of 
adaptor proteins to mediate a variety of cellular processes including ER 
associated degradation, autophagy and DNA damage repair.

Successful candidates must hold a PhD in a structural biology or biochemistry 
discipline or an equivalent level of research, industrial or commercial 
experience and have demonstrated capacity for innovative high quality 
structural biological research. Previous research experience in a structural 
biological laboratory environment covering X-ray crystallography or electron 
microscopy single particle analysis is essential. The successful candidate must 
also have an advanced knowledge of protein biochemistry and structural biology. 
Experience in supervision and training of junior research staff and students 
and in writing scientific research papers would be advantageous.

The successful candidate must be able to work effectively within a team, have 
the ability to develop and apply new concepts, and have a creative approach to 
problem-solving. They will also be expected to demonstrate excellent verbal and 
written communication skills, and be able to write clearly and succinctly for 
publication.

For informal enquiries please contact Professor Paul Freemont 
(p.freem...@imperial.ac.uk) or Professor Xiaodong Zhang 
(xiaodong.zh...@imperial.ac.uk)

Our preferred method of application is online via our website 
http://www3.imperial.ac.uk/employment (please select “Job Search” then enter 
the job title or vacancy reference number – NS 2012 047 IL - including spaces 
into “Keywords”).  Please complete and upload an application form as directed.

 

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Professor Paul Freemont

Co-director of Macromolecular Structure and Function Group
Department of Life Sciences
Sir Ernst Chain Building - Wolfson Laboratories
South Kensington Campus
London SW7 2AZ, UK
www.msf.bio.ic.ac.uk

Tel: 02075945327
Email: p.freem...@imperial.ac.uk

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