A postdoc position is available in the group of Alex Bullock, University of 
Oxford, to study the structural and chemical biology of E3 Ligases as part of 
the EU-funded "EUbOpen" consortium, with funding until 30 April 2025. The 
project will support the next generation of PROTACs/molecular glues for 
targeted protein degradation.
Nature Reviews Drug Discovery volume 18, pages 949-963 (2019)
https://www.nature.com/articles/s41573-019-0047-y

The postholder will optimise purification and crystallisation systems for human 
Cullin-RING E3 ligase substrate adaptor proteins, solve their structures and 
study their interactions with substrate proteins, peptides and low molecular 
weight compounds. The post will involve significant collaborative teamwork 
internally, as well as with external academic and industry partners.

Applications close at noon 10 November 2021. Full details are available here:
Job Details 
(corehr.com)<https://my.corehr.com/pls/uoxrecruit/erq_jobspec_version_4.display_form?p_company=10&p_internal_external=E&p_display_in_irish=N&p_process_type=&p_applicant_no=&p_form_profile_detail=&p_display_apply_ind=Y&p_refresh_search=Y&p_recruitment_id=153890>

Informal enquires can be sent to 
alex.bull...@cmd.ox.ac.uk<mailto:alex.bull...@cmd.ox.ac.uk>

https://www.cmd.ox.ac.uk/team/alex-bullock
https://www.cmd.ox.ac.uk/research/growth-factor-signalling-and-ubiquitination



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