July 2009 13:35
To: CCP4BB@JISCMAIL.AC.UK
Subject: Re: [ccp4bb] Problem with different map when ligand
refinement
Is the correct ligand HOCH2CH(CH3)C(O)SCH3? The ligand
depicted in the density map is HOCH2CH(CH3)C(O)OCH3.
Cheers, Roger Rowlett
Ngo Duc Tri wrote:
Dear ccp4
Hi,
Barring orientation mishaps - it almost sounds like you have an ethyl
rather than a methyl ester...
Could it be that your compound is an ester of ethanol rather than methanol?
Artem
Dear ccp4 experts,
I am trying to solve the structure of one esterase with its substrate. The
structure
Dear TriNigo
I would put waters in all the other difference density first (there
are several obvious waters even in the section of map you sent with
your email), without the substrate, and see if you see any more clues
as to what's going on. Do you expect something to be added on the
