Re: [ccp4bb] Refining alt. confs for only part of a ligand

Hi Nick, Pavel and Herman, Thanks for the lightning-fast tip about not using an altconf label for the common part of the molecule. That was the solution. So obvious when you think about it... My colleague Esko Oksanen also pointed out offline that I need to include the last atom before the

Re: [ccp4bb] Refining alt. confs for only part of a ligand

Conformer A atoms don’t “see” conformer B atoms so as far as the program is concerned the B conformer only has the last ring. You should set all confA atoms not in the last ring to blank conformers. So: last ring - A +B conformers rest of ligand - no conformer Thanks, Nick —