Dear colleagues, This is to remind you about the upcoming CNIO Frontiers Meeting on Allosteric Regulation of Cell Signalling in Madrid, on 17-19 September 2012. Further, in light of the economic difficulties many scientists are facing, we are offering subscriptions at reduced cost:
Students and CSIC members: 50 € Companies: 200 € Others 100 € (VAT included) This meeting will bring together world-leading scientists from different backgrounds (see list of speakers below), in particular structural biology, molecular dynamics and drug discovery. For registration, abstract submission and further information, see: http://www.cnio.es/eventos/index.asp?ev=1 This CNIO Frontier Meeting aims to discuss different aspects of allosteric mechanisms that regulate signalling pathways involved in cancer. The talks will cover i) Introduction to allostery (by Jean Pierre Changeaux, one of the founding fathers of the theory of allostery) ii) the diversity of allosteric mechanisms in cell signalling, iii) protein dynamics in allostery and iv) allosteric drug targeting for therapy. Organisers: *Francesco Gervasio, *CNIO, Madrid, Spain *Daniel Lietha, *CNIO, Madrid, Spain *Ermanno Gherardi, *MRC Laboratory of Molecular Biology, Cambridge, UK *Giulio Superti-Furga, *CeMM, Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria *Confirmed Speakers:* *Jean Pierre Changeux,* Collège de France, Institut Pasteur, France ***Roger Sunahara, *University of Michigan Medical School, USA *Timothy A. Springer,* Harvard Medical School, USA *Yvonne Jones, *University of Oxford, UK *Tom L. Blundell, *University of Cambridge, UK *Alfred Wittinghofer, *MPI for Molecular Physiology, Dortmund, Germany *Guillermo Montoya, *CNIO, Spain *Susan S Taylor, *UCSD, USA *Daniel Leahy, *Johns Hopkins University, USA *Gerhard Hummer*, NIH Bethesda, USA *Ruth Nussinov, *NCI Frederick, USA *Nikolay V. Dokholyan, *School of Medicine University of North Carolina, USA *Jose Onuchic, *Center for Theoretical Biological Physics at Rice and UCSD*, *La Jolla, USA *Dorothee Kern, *Brandais University, USA *Alfonso Valencia, *CNIO, Spain *Michael J. Eck, *Dana-Farber Cancer Institute, Harvard Medical School, USA *Markus G. Grütter*, University of Zurich, Switzerland *Françoise Bono,* SANOFI AVENTIS SA, Toulouse, France *Jeffrey R. Peterson, *Fox Chase Cancer Center Philadelphia, USA *Doriano Fabbro,* Novartis Pharma AG, Basel, Switzerland Best regards, Francesco Gervasio and Daniel Lietha
