Job Title Research Associate in X-ray Protein Crystallography of Light Induced Reactions

Department/Division/Faculty Division of Molecular Biosciences, Faculty of Natural Sciences
South Kensington Campus, London SW7 2AZ


Closing Date 1 June 2010 (midnight GMT/BST)
Fixed term for 24 months

Applications are invited for a Research Associate position in the Division of Molecular Biosciences in the field of time resolved Laue X-ray crystallography of light sensitive proteins in the group of Dr. Jasper van Thor. The successful candidate will develop and employ experiments for time resolved X-ray diffraction using the pink-Laue technique at specialised beam line stations that combine pulsed broadband hard X-rays with pulsed optical excitation, at the SLS, APS and ESRF. The post will be based at Imperial College London, South Kensington campus

The work will be conducted in a multidisciplinary environment which includes facilities for ultrafast electronic and vibrational spectroscopies to support the optical control of photolysis and reaction initiation in macromolecular crystals.

The research deals with the light induced reactions in photoreceptors and fluorescent proteins and will focus on crystallisation of existing and new targets, analysis and optimisation of Laue diffraction, data processing and structure calculation of sub-ns intermediates. The van Thor group also provides support for ultrafast spectroscopic investigation of light induced reactions in targets. You will be required to work with members of the team on spectroscopic characterisation and photolysis control.

You will have a PhD in Biochemistry, Chemistry, or Physics or the equivalent professional qualifications and experience with a track record in Structural Biology. Extensive experience in X-ray protein crystallography using synchrotron sources as well as experience with data processing and structure calculation of macromolecules are essential.

You will also have experience in crystallographic data processing and structure calculation. Experience in biomolecular spectroscopy would be an advantage. Experience with molecular biology, protein purification and crystallisation will be desirable.



Our preferred method of application is online via this website. Please download the following application form and save to your computer. Once completed, please upload your application form prior to submitting your application.

Please enter job ID NS2010070AB into the College recruiting webpages

http://www3.imperial.ac.uk/employment

or directly

https://www4.ad.ic.ac.uk/OA_HTML/OA.jsp?akRegionCode=IRC_VIS_VAC_DISPLAY_PAGE&akRegionApplicationId=800&transactionid=1751883119&retainAM=Y&addBreadCrumb=S&p_svid=17014&p_spid=862010&oapc=7&oas=gMemD704ZdjaWC14QWLTmA..

Should you have any queries please contact:

Dr Jasper van Thor – j.vant...@imperial.ac.uk

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Jasper van Thor
Royal Society University Research Fellow
Division of Molecular Biosciences South Kensington Campus Imperial College London London SW7 2AZ, UK
Email j.vant...@imperial.ac.uk
Phone +44-(0)20-75945071
http://www3.imperial.ac.uk/people/j.vanthor

SOON: One Day Symposium on Ultrafast Vibrational Dynamics of Biomolecules, Thursday 29 April 2010 at Imperial College
http://www3.imperial.ac.uk/molecularbiosciences/seminars/ultrafast-vibrational-dynamics-of-biomolecules

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