Two PhD positions in the group of Titia Sixma at the Netherlands Cancer 
Institute in Amsterdam to study processes at the interface of DNA repair and 
replication using cryo-EM and quantitative biochemistry 
(https://www.nki.nl/research/research-groups/titia-sixma/).

These are both Marie Sklodowska-Curie Action doctoral networks, one is the 
REPLIFATE project (https://replifate.eu), where we focus on regulation of DNA 
replication by PTMs during cell fate decisions (project 4). Please apply 
through the Replifate website, deadline is January 15, 2023, on-line interviews 
will be end of February.

The other project is the REPSTATE project, where we study defined states of 
human DNA mismatch repair proteins, structurally, biochemically and 
biophysically. Applications can be made directly to Titia Sixma 
(t.si...@nki.nl);

Marie Curie projects involve close collaboration with partner labs and 
industrial partners. The Netherlands Cancer institute is an international 
center of excellence with a high standard of biological research and 
outstanding research facilities, with an interactive atmosphere. It is located 
in Amsterdam, with all its cultural amenities, close to the Schiphol airport. 
We share labspace and equipment with Anastassis (Tassos) Perrakis and Robbie 
Joosten, ensuring a lively structural biology community.

Both projects follow EU mobility rules: This means that the candidate must not 
have resided or carried out their main activity (work, studies etc) in the 
Netherlands for more than 12 months in the 36 months immediately before the 
recruitment date (=first day of employment).




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