Dear Structural Biology community,
I would be grateful if you could please bring the following postdoctoral
position to the attention of potential candidates.
Kindest regards
Much obliged
Doriano Lamba
Two years post-doc position to work on the structural characterization
of protein involved in chronic pain (Scuola Normale Superiore - Pisa,
Italy and Institute of Crystallography at CNR, Trieste, Italy)
Research contract: “Dissecting NGF Interactions with TrkA Receptor:
Structural Studies of complexes with two Neutralizing Antibodies of
therapeutic relevance in chronic pain” on the following European
project: "The NGF system and its interplay with endocannabinoid
signalling, from peripheral sensory terminals to the brain: new targets
for the development of next generation drugs for neuropathic pain”
We are seeking a highly motivated and enthusiastic post-doc to perform
structural studies on molecules of the Nerve Growth Factor (NGF)
receptor family and on their antibodies.
The position will be in the group of Antonino Cattaneo at Scuola Normale
Superiore (Pisa) and of Doriano Lamba at the Institute of
Crystallography in Trieste.
The Joint groups have a considerable experience in the structural
characterization of proteins relevant for neurodegeneration and chronic
pain.
The experimental work will be performed mostly in Trieste.
In this EU funded three-years project (PAINCAGE) the SNS/CNR team will
perform the biophysical and structural characterization of complexes
between the antiTrkA MNAC13 antibodies in Fab format and the two
immunoglobulin-like domains d4-d5 of TrkA and between the antiNGF αD11
antibodies in Fab format and NGF. Moreover the team will perform the
structural characterization of the NGFR100 HSAN V mutant.
The ideal candidate will have strong skills in molecular biology,
protein expression, biochemistry and biophysics/structural biology.
Experience in X-ray protein crystallography and/or Small Angle X-ray
Scattering are a plus. The candidate should be highly motivated, work
well as a team, have excellent communication skills, and a strong
publication record.
Duration of the contract: 2 years (estimated starting: July/August 2014)
Gross compensation inclusive of all taxes: € 47.630,00
Application deadline:July 2nd 2014
To apply please visit:
Italian: http://www.sns.it/servizi/job/assegnidiricerca/assegno254/
English: http://www.sns.it/en/servizi/job/assegnidiricerca/assegno254/
For further information please contact:
Dr. Doriano Lamba
Phone +39 040 375 8514
E-mail: doriano.la...@ts.ic.cnr.it
