Two postdoctoral positions are available in the group of Alex Bullock, University of Oxford. The posts will support the EU-funded "EUbOpen" consortium that aims to generate chemical inhibitors for druggable protein families, including ubiquitin ligases (E3s) and solute carriers (SLCs). Both posts will involve significant collaborative teamwork between partners from academia and industry. Enquires can be sent to alex.bull...@cmd.ox.ac.uk<mailto:alex.bull...@cmd.ox.ac.uk>
(1) Postdoctoral Scientist, Structural and Chemical Biology of E3 Ligases The postholder will optimise efficient expression, purification and crystallisation systems for novel human E3 ligase proteins and study their interactions with substrate proteins, peptides and low molecular weight compounds. Structures will be determined with the goal to develop highly selective chemical probe molecules. This post is offered full-time on a fixed term contract until 30 April 2025. Applications close at noon 9 August 2021. Full details are available here Job Details (corehr.com)<https://my.corehr.com/pls/uoxrecruit/erq_jobspec_version_4.display_form?p_company=10&p_internal_external=E&p_display_in_irish=N&p_process_type=&p_applicant_no=&p_form_profile_detail=&p_display_apply_ind=Y&p_refresh_search=Y&p_recruitment_id=152015> (2) Postdoctoral Scientist, Chemical Biology Assays The postholder will design and optimise biochemical and cellular assays to screen protein targets of different classes against small molecule compound collections and validate hits with orthogonal biophysical assays. Opportunity also exists for further structural and functional studies. You will work independently and as part of a team to complete research projects and draw conclusions from analysing all available data. This post is offered full-time on a fixed term contract until 30 April 2025. Applications close at noon 4th August 2021. Full details are available here Job Details (corehr.com)<https://my.corehr.com/pls/uoxrecruit/erq_jobspec_version_4.display_form?p_company=10&p_internal_external=E&p_display_in_irish=N&p_process_type=&p_applicant_no=&p_form_profile_detail=&p_display_apply_ind=Y&p_refresh_search=Y&p_recruitment_id=152014> ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
