Dear colleagues,
Two postdoctoral positions are available at The University of British Columbia in Vancouver, Canada: *Position 1:* A postdoctoral position is available immediately to work on ion channel structural biology in the lab of Filip Van Petegem, Department of Biochemistry and Molecular Biology. The project combines X-ray crystallography, cryo-EM, and electrophysiology. Our lab has steady access to the in-house X-ray and cryo-EM facilities: - Microscopes: 300kV Titan Krios with Falcon IV detector and Selectris Energy filter. A 200kV Glacios (Falcon III detector) is available for prescreening grids. - X-ray equipment in the lab includes Mosquito and Dragonfly robotics, and we have regular access to an in-house X-ray diffractor (Rigaku Micromax-007 HF with Saturn 744+ CCD detector) and various synchrotron beamlines Minimum requirement for applicants include a PhD in Biochemistry or a related discipline with extensive experience in either X-ray crystallography or cryo-EM, as well as protein expression and purification. Direct experience with membrane proteins is an additional plus. The lab values diversity and inclusivity, and applicants from all backgrounds are encouraged to apply. This is an opportunity for people with structural biology expertise to learn electrophysiological methods. Recent work from the lab includes an investigation of how Ryanodine Receptors are modulated by small molecules, disease mutations, and post-translational modification, using cryo-EM, X-ray crystallography, planar lipid bilayer electrophysiology, and enzyme kinetics. Woll et al (2021) *Nature Comm.* 12:807 Ma et al (2020) *Nat Chem Biol*. 16,1246-1254 Haji-Ghassemi et al (2019) *Molecular Cell* 75,1-14 For more information on recent work, see http://crg.ubc.ca/VanPetegem/ The lab is housed within the Life Sciences Centre at UBC (lsi.ubc.ca), located on the Point Grey campus in Vancouver. Interested candidates should send a CV, along with names and contact details for 3 references to *filip.vanpete...@gmail.com <filip.vanpete...@gmail.com>*. -------------- *Position 2:* A postdoctoral position is available to work on a joint project between the labs of Filip Van Petegem and Robert Molday, both in the Department of Biochemistry and Molecular Biology at the University of British Columbia. The project will involve Cryo-EM on neuronal membrane proteins and will make use of the excellent cryo-EM facility within the Life Sciences Institute. Microscopes available include a 300kV Titan Krios with Falcon IV detector and Selectris Energy filter. A 200kV Glacios (Falcon III) is available for prescreening grids. The structural biology will be complemented with various functional assays. The ideal candidate will have a PhD in Biochemistry or a related discipline, as well as extensive experience with either X-ray crystallography and/or Cryo-electron microscopy. Direct experience with membrane protein expression and mammalian cell cultures is an additional asset. The Molday and Van Petegem labs are housed within the Life Sciences Institute (https://lsi.ubc.ca/). For more information on the labs, see http://crg.ubc.ca/VanPetegem/ and https://biochem.ubc.ca/person/robert-molday/ Interested candidates should send a CV, along with names and contact details for 3 references to both mol...@mail.ubc.ca and filip.vanpete...@gmail.com. -- Filip Van Petegem, PhD Professor, Dept. of Biochemistry and Molecular Biology The University of British Columbia 2350 Health Sciences Mall - Rm 2.356 Vancouver, V6T 1Z3 phone: +1 604 827 4267 email: filip.vanpete...@gmail.com http://crg.ubc.ca/VanPetegem/ Twitter: @FilipPetegem ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/