ailto:CCP4BB@JISCMAIL.AC.UK] On Behalf Of Edward
> A. Berry
> Sent: Friday, 9 June 2017 2:53 AM
> To: CCP4BB@JISCMAIL.AC.UK
> Subject: Re: [ccp4bb] preparing DL-Malic acid stock solution
>
> (di)Sodium D,L-malate is available from Sigma-Aldrich (# CDS023113) and
> pro
] preparing DL-Malic acid stock solution
(di)Sodium D,L-malate is available from Sigma-Aldrich (# CDS023113) and
probably dissolves to give a 3M solution which is slightly alkaline.
If pK2 is 5.1, then an insignificant amt of malic acid should bring the
pH down to 7 (If you have to add a significant
(di)Sodium D,L-malate is available from Sigma-Aldrich (# CDS023113) and
probably dissolves to give a 3M solution which is slightly alkaline.
If pK2 is 5.1, then an insignificant amt of malic acid should bring the
pH down to 7 (If you have to add a significant amount, just add more
water to dilute
As the pKa1 of malic acid is 3.4, it may be that the partially neutralized
malic acid salt is less soluble than the acid or the fully neutralized salt.
The pKa2 of malic acid is 5.1.
Contact the people at Hampton Research
https://www.hamptonresearch.com/contact_us.aspx
and ask them. They sell
Dear all,
we’ve recently having trouble preparing a 3 M stock solution of DL-Malic Acid,
pH 7 (which we had, so it’s doable!).
When we reach pH 3 - 4 the solution turns milky white and does not goes back to
a clear solution even when the pH is raised.
Does anybody have any advice on how to get