Dear Folks,
The last novel proteins fold were from the yr 2007(pdb statistics),
>From 2007 to till date no novel fold has been identified, this mean the
present 1283 fold are the final or
should I wait, if so , with what criteria do I expect for a new fold..or
what are the expectations ...
If we
Jayashankar wrote:
Dear Folks,
Dear gmail-user,
The last novel proteins fold were from the yr 2007(pdb statistics),
From 2007 to till date no novel fold has been identified, this mean
the present 1283 fold are the final or
should I wait, if so , with what criteria do I expect for a new
fol
But provided if i colud follow a pattern even blindfolded could come up with
some probable things.
Is it not ok to have principle of mathematical induction.
S.Jayashankar
Research Student
Institute for Biophysical Chemistry
Hannover Medical School
Germany.
On Wed, Feb 25, 2009 at 7:07 PM, Pau
On Wednesday 25 February 2009 08:20:14 Jayashankar wrote:
> Dear Folks,
>
> The last novel proteins fold were from the yr 2007(pdb statistics),
> From 2007 to till date no novel fold has been identified,
If you reached this conclusion by looking at the PDB web site,
you should note that the site
As an outsider to this field, it would seem another way to approach it
would be to ask, of the currently known folds, how many have only one
member (excluding evolutionarily related protein families)?
If a large number of folds have only been sampled once, it is likely
that there are others that
What happens when a single protein strays from the fold?
Jacob
- Original Message -
From: "Edward A. Berry"
To:
Sent: Wednesday, February 25, 2009 2:48 PM
Subject: Re: [ccp4bb] protein folds
As an outsider to this field, it would seem another way to approach it
would
cob
Keller
Sent: Wednesday, February 25, 2009 4:04 PM
To: CCP4BB@JISCMAIL.AC.UK
Subject: Re: [ccp4bb] protein folds
What happens when a single protein strays from the fold?
Jacob
- Original Message -
From: "Edward A. Berry"
To:
Sent: Wednesday, February 25, 2009 2:48 PM
From: CCP4 bulletin board [mailto:ccp...@jiscmail.ac.uk] On Behalf Of Edward
A. Berry
Sent: Wednesday, February 25, 2009 3:49 PM
To: CCP4BB@JISCMAIL.AC.UK
Subject: Re: [ccp4bb] protein folds
As an outsider to this field, it would seem another way to approach it
would be to ask, of the currently
Paul Emsley wrote:
Here's an experiment:
Find a blindfold and put it on. Oh, but before you do that, take a
map of England and place it on a dartboard.
Now take 56066 darts and throw them at the map on the board.
Take off the blindfold and investigate where the darts hit. Did you
hit all the
Must be even smaller than Daresbury then. They don't even have a
synchrotron!
Bart
James Holton wrote:
Paul Emsley wrote:
Here's an experiment:
Find a blindfold and put it on. Oh, but before you do that, take a
map of England and place it on a dartboard.
Now take 56066 darts and throw them
CCP4 bulletin board wrote on 02/25/2009 03:08:10
PM:
> On Wednesday 25 February 2009 08:20:14 Jayashankar wrote:
> > Dear Folks,
> >
> > The last novel proteins fold were from the yr 2007(pdb statistics),
> > From 2007 to till date no novel fold has been identified,
>
> If you reached this conclu
The original poster may be interested in this paper from Phil Bourne's
lab a few years ago which looked at the contribution of folds (among
other things) by the Protein Structure Initiative, particularly Fig 5
and table 1.
http://helix-web.stanford.edu/psb04/bourne.pdf
"The Status of Structural G
Concerning the number of proteins folds in existence vs. the number of
folds already identified:
Ed Berry had some good points regarding sample statistics, and I assume
the mathematics of that sort of thing is formalized somewhere. The
number of examples per protein fold will be skewed by the comm
On Feb 25, 2009, at 11:45 AM, Jayashankar wrote:
But provided if i colud follow a pattern even blindfolded could come
up with some probable things.
Is it not ok to have principle of mathematical induction.
Or extrapolation. I would make a plot of new folds discovered by year
and extrapola
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