[CMLHope] Re: Fwd: 13 yr old son diagnosed in August

2008-11-04 Thread Trey
Generally, Gleevec does the same things to children that it does to adults. But that lack of long term history with the drug prevents knowing what will happen over a very long term. But then, 7 1/2 years plus the clinical trial period of several more years does provide a lot of evidence that Gle

[CMLHope] Re: Fwd: 13 yr old son diagnosed in August

2008-11-04 Thread Sandy Collins
Trey, Thank you so much for your input and the wealth of information! Nick does have 2 siblings and neither one of them are a match...all of us were tested and none of us matched. There is 11 "potential" donors in the National Marrow Bank and they are being contacted to undergo additional testing.

[CMLHope] Re: Fwd: 13 yr old son diagnosed in August

2008-11-03 Thread Trey
The difference of opinion mainly comes from a relatively short history of Gleevec, some 7 1/2 years now. That lack of history makes many Oncs nervous about predicting very long term success of the CML drugs, even though they show great results so far. BMT has become a last resort for adults, but