I, too, was originially put on Interferon and among all the extremely nasty side-effects, one is peripheral myopathy, which means that the nerves and blood vessels in the bottom of the feet are affected and the bottom of the feet may become numb. This is not completely reversible but since I was also having extremely painful cramps and spasms in my lower legs, I was put on Pletal/generic: Cilostazol. I am told that it does not work for everyone but it certainly did help me, reducing the cramps and spasms in my legs and feet and restoring a certain amount of feeling in the soles of my feet. If anyone on interferon or on Gleevec has these side-effects they should be addressed in a serious manner. I know some people have been taking or drinking quinine for the leg cramps. Quinine should not be used if one has tinnitus since quinine exacerbates the tinnitus. Vivi --~--~---------~--~----~------------~-------~--~----~ [CMLHope] A support group of http://cmlhope.com -------------------------------------------------
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