-Caveat Lector-

Monday October 11 2:52 PM ET
Brain Shocks May Help Depression
By LAURAN NEERGAARD AP Medical Writer

WASHINGTON (AP) - The former shipbuilder had severe depression unrelieved by
any of today's therapies, so sick he had trouble even leaving his house.
Then
doctors implanted a pacemaker-like device to stimulate a part of his brain
thought important for mood - and that very day the man laughed.

``It was remarkable,'' recalled Dr. Mark George of the Medical University of
South Carolina, who performed the experimental implant. ``I said, 'Are you
being forced to laugh or do you feel good inside?' He said both.''

Stimulating a nerve that runs from the neck into one of the brain's most
mysterious regions appears promising enough at relieving once-untreatable
depression that the government just granted permission for a study at 15
hospitals around the country.

The treatment, called vagus nerve stimulation, involves sending tiny
electric
shocks into the vagus nerve in the neck, where it then relays messages deep
into the brain.

About half of the 30 depressed patients treated in a pilot study - people
who
had failed every other treatment - ``got a very good response,'' George said
in
an interview.

The results are not definitive, he cautioned. But he added, ``Stimulating
there
really is a wonderful portal into the base of the brain.''

Full text at:
http://dailynews.yahoo.com/h/ap/19991011/hl/brain_stimulator_2.html

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