-Caveat Lector-

http://www.infobeat.com/stories/cgi/story.cgi?id=2559425333-2a0

04:20 PM ET 05/04/99

Dioxin Exposure Linked to Cancer

 Dioxin Exposure Linked to Cancer
 By PAUL RECER=
 AP Science Writer=
           WASHINGTON (AP) _ Chemical workers exposed to high levels of
 dioxin have a 60 percent increased chance of dying of cancer, but
 the chemical poses no added cancer risk to the general population,
 a study says.
           Kyle Steenland, co-author of the study appearing Wednesday in
 the Journal of the National Cancer Institute, said the research
 suggests most people typically are not currently exposed to
 dangerous levels of dioxin and that cancer appears to result only
 among those who had extremely high and long-term exposures to the
 chemical 15 to 20 years ago.
           ``There is not a significant increase in cancers until you get
 to the upper'' exposure levels, Steenland said Tuesday in a
 telephone interview. ``This is not raising a red flag by saying
 that low level exposure is causing a lot of cancer.''
           He called the finding ``reassuring'' from a public health stand
 point.
           Steenland, a researcher with the National Institute for
 Occupational Safety and Health, said that the amount of dioxin in
 the environment is steadily declining because the products most
 commonly linked to the chemical are no longer being made.
           Dioxin was a byproduct in the manufacture of herbicides and
 pesticides that were in common use decades ago. Production of the
 chemicals halted in the mid 1980s, and the environmental
 contamination has dropped steadily since.
           However, for those who experienced high exposures, the chemical
 can persist in the body for decades.
           Dioxin is one of the chemicals in Agent Orange, the herbicide
 used by the United States to kill jungle vegetation during the
 Vietnam War. Hundreds of American troops were exposed to the
 chemical, but not at the high levels experienced by many chemical
 plant workers, said Steenland.
           Dr. Robert N. Hoover, of the National Cancer Institute, said
 that the study by Steenland and his colleagues is ``a critical
 piece of evidence'' that shows dioxin, at its present levels in the
 environment, appears to present no significant threat to general
 public health.
           ``The bad news from this study is the evidence that dioxin at
 high exposures is a'' cancer-causing chemical, said Hoover. ``The
 good news is that the low levels of exposure (now in the
 environment) are not likely to contribute much disease.''
           In the study, Steenland examined the health record of some 3,500
 chemical workers who were exposed to dioxin on the job during the
 1960s, '70s and '80s for periods of six months to 20 years.
           Among workers with the highest exposure rate there was a 60
 percent increase in cancer deaths when compared to the rate of
 cancer deaths among the general public. This increase, said
 Steenland, was seen only in those workers whose dioxin exposure was
 100 to 1,000 times higher than the background exposure of the
 general public.
           Steenland said that dioxin seemed to cause all types of cancer.
           ``The cancer elevation is not in some specific organ,'' he said.
 ``We saw it in respiratory tract cancers and in digestive tract
 cancer. It was across the board.''
           Steenland said the public health threat of dioxin is declining
 because nobody is regularly exposed to the high levels that once
 were common among chemical plant workers.
           ``Dioxin is not being added to the environment at anywhere near
 the rate it once was,'' he said. ``It is still produced by
 incinerators when they burn plastics, but it is becoming less and
 less.''

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