In a message dated 5/16/00 3:00:47 PM Central Daylight Time, AOL News writes:

<< Subj:    Researchers Warn of TB Epidemic
 Date:  5/16/00 3:00:47 PM Central Daylight Time
 From:  AOL News
 BCC:   Ahab42

 Researchers Warn of TB Epidemic

 .c The Associated Press

  By MARTHA IRVINE

 Associated Press

 CHICAGO (AP) - A small but alarming percentage of people worldwide have a
form of tuberculosis that is resistant to the usual treatments and must be
fought with stronger, more expensive drugs to prevent a health crisis
comparable to AIDS, World Health Organization researchers say.

 ``If we don't encourage countries to do a good treatment of TB, then we will
have an epidemic on our hands,'' said Dr. Marcos Espinal, who led a study
published in Wednesday's Journal of the American Medical Association.

 TB is a contagious respiratory disease that kills an estimated 2 million
people a year. If treated correctly, most cases are curable.

 The study examined 6,402 TB cases at clinics in Russia, Peru, China, South
Korea and the Dominican Republic between 1994 and 1996 and found that about
5.5 percent did not respond to so-called first-line drugs.

 Drugs that could effectively treat these patients are much more expensive
and have to be taken for up to two years - potential barriers in some poor,
developing countries.

 But failing to treat these patients could have catastrophic results,
particularly since TB tends to mutate into even more resistant strains when
treated incorrectly, said Espinal, a doctor with WHO's communicable diseases
program in Switzerland.

 If more countries do not correctly treat TB, the organization estimates that
nearly 1 billion people will be newly infected - and 35 million will die - in
the next two decades.

 In the United States from 1993 through 1998, 45 states and the District of
Columbia reported at least one case each of multi-drug-resistant TB,
according to the Centers for Disease Control and Prevention.

 While TB more commonly afflicts people in poorer, developing countries,
Espinal warned that because it is an airborne disease, ``TB can be in eight
hours from Russia to New York.''

 Another researcher agreed with Espinal's prognosis and called drug-resistant
TB a ``public health emergency.''

 ``The genie of multi-drug-resistant TB is irreversibly out of the bottle,''
Dr. C. Robert Horsburgh of Boston University's Schools of Public Health and
Medicine wrote in an accompanying editorial.

 Espinal said 119 of the 212 WHO member countries, including the United
States, have implemented or agreed to implement the organization's
TB-fighting plan, which calls for treatment with the first-line drugs.
Twenty-two countries representing 85 percent of all TB cases - including
China, India, Brazil and Nigeria - have agreed to take part.

 WHO is also calling for an expansion of the TB-fighting plan using
treatments that are at least 350 more times more expensive than first-line
drugs such as isoniazid and rifampicin, which cost $20 to $30.

 Already, India's health secretary has said that with an annual 2 million new
cases in India alone, his government cannot keep pace with the costs,
estimated at $55 million this year.

 WHO estimates that 16 million people worldwide have tuberculosis, and rates
of infection are on the rise. WHO officials estimate there were 8 million new
cases of TB in 1997 alone. The United States had 18,361 reported cases in
1998, according to the CDC.

 On the Net: World Health Organization:
http://www.who.int/health-topics/tb.htm

 AP-NY-05-16-00 1600EDT

  Copyright 2000 The Associated Press.  The information  contained in the AP
news report may not be published,  broadcast, rewritten or otherwise
distributed without  prior written authority of The Associated Press.



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Researchers Warn of TB Epidemic

.c The Associated Press

 By MARTHA IRVINE

Associated Press

CHICAGO (AP) - A small but alarming percentage of people worldwide have a form of 
tuberculosis that is resistant to the usual treatments and must be fought with 
stronger, more expensive drugs to prevent a health crisis comparable to AIDS, World 
Health Organization researchers say.

``If we don't encourage countries to do a good treatment of TB, then we will have an 
epidemic on our hands,'' said Dr. Marcos Espinal, who led a study published in 
Wednesday's Journal of the American Medical Association.

TB is a contagious respiratory disease that kills an estimated 2 million people a 
year. If treated correctly, most cases are curable.

The study examined 6,402 TB cases at clinics in Russia, Peru, China, South Korea and 
the Dominican Republic between 1994 and 1996 and found that about 5.5 percent did not 
respond to so-called first-line drugs.

Drugs that could effectively treat these patients are much more expensive and have to 
be taken for up to two years - potential barriers in some poor, developing countries.

But failing to treat these patients could have catastrophic results, particularly 
since TB tends to mutate into even more resistant strains when treated incorrectly, 
said Espinal, a doctor with WHO's communicable diseases program in Switzerland.

If more countries do not correctly treat TB, the organization estimates that nearly 1 
billion people will be newly infected - and 35 million will die - in the next two 
decades.

In the United States from 1993 through 1998, 45 states and the District of Columbia 
reported at least one case each of multi-drug-resistant TB, according to the Centers 
for Disease Control and Prevention.

While TB more commonly afflicts people in poorer, developing countries, Espinal warned 
that because it is an airborne disease, ``TB can be in eight hours from Russia to New 
York.''

Another researcher agreed with Espinal's prognosis and called drug-resistant TB a 
``public health emergency.''

``The genie of multi-drug-resistant TB is irreversibly out of the bottle,'' Dr. C. 
Robert Horsburgh of Boston University's Schools of Public Health and Medicine wrote in 
an accompanying editorial.

Espinal said 119 of the 212 WHO member countries, including the United States, have 
implemented or agreed to implement the organization's TB-fighting plan, which calls 
for treatment with the first-line drugs. Twenty-two countries representing 85 percent 
of all TB cases - including China, India, Brazil and Nigeria - have agreed to take 
part.

WHO is also calling for an expansion of the TB-fighting plan using treatments that are 
at least 350 more times more expensive than first-line drugs such as isoniazid and 
rifampicin, which cost $20 to $30.

Already, India's health secretary has said that with an annual 2 million new cases in 
India alone, his government cannot keep pace with the costs, estimated at $55 million 
this year.

WHO estimates that 16 million people worldwide have tuberculosis, and rates of 
infection are on the rise. WHO officials estimate there were 8 million new cases of TB 
in 1997 alone. The United States had 18,361 reported cases in 1998, according to the 
CDC.

On the Net: World Health Organization: http://www.who.int/health-topics/tb.htm

AP-NY-05-16-00 1600EDT

 Copyright 2000 The Associated Press.  The information  contained in the AP news 
report may not be published,  broadcast, rewritten or otherwise distributed without  
prior written authority of The Associated Press.



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Reuters articles to your daily news delivery, go to KW: <A HREF="aol://5862:146">News 
Profiles</A> and click on "Modify Your News Profiles." Then click "Edit" and add 
Reuters from the list on the left.

To edit your profile, go to keyword <A HREF="aol://1722:NewsProfiles">NewsProfiles</A>.
For all of today's news, go to keyword <A HREF="aol://1722:News">News</A>.


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