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WSWS : News & Analysis : Medicine & Health : BSE/CJD

Britain: Deaths from Human BSE reveal "statistically significant rising trend"
By Richard Tyler
20 July 2000
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Two more deaths in the last fortnight have brought to 69 the total number of
fatalities in the UK from variant Cretzfeld Jakob Disease (vCJD). So far this
year 14 people have died from this brain-wasting disorder related to BSE
(Bovine Spongiform Encephalopathy) or Mad Cow disease, equalling the 1999
total. Another seven are known to be currently suffering from this incurable
disease, also known as Human BSE.

Government scientists warned Monday that there was a “statistically
significant rising trend” in the number of vCJD victims. The government's
Spongiform Encephalopathy Advisory Committee (SEAC), set up in the wake of
the emergence of BSE during the mid-1980s, put the increase at between 20 and
30 percent a year.

The World Socialist Web Site spoke to a number of relatives of Human BSE
victims. Gerard Callaghan's brother Maurice died of the disease in November
1995. He said the rising trend was “very worrying. It is something that as a
group of families has concerned us greatly.”

The Labour government has earmarked just £26 million for research into CJD
and BSE, a fraction of the amount that has been paid to farmers in
compensation for cattle that were culled. In March, Prime Minister Tony Blair
announced that over £200 million in further assistance would be paid to UK
farmers. This comes on top of over £270 million in compensation paid to
farmers in 1998 and 1999 alone.

Asked what he thought of the measures that had been introduced since Labour
came to power in 1997, Gerhard Callaghan said, “I have little or no
confidence in them. The fact is that we still have widespread abuses. An
Irish farmer was recently prosecuted for deliberately importing an
BSE-infected animal to get government compensation. The system is really open
to abuse.”

John Middleton, whose son Mathew Parker died of Human BSE in March 1997 at
the age of 19, said he thought the government was still playing down the true
level of the disease. “They don't want to damage the beef industry. It seems
to me that animals are better thought of than humans. They are spending all
that money on compensation to farmers and nothing for the families of victims
of Human BSE. Personally, I would rather have my son back, but it's the
principle of the thing.”

Frances Hall of the Human BSE Foundation, whose son Peter was among the first
victims of the disease, said, “It has been apparent to us for some time now
that the numbers were going up. I run a help line and it has been obvious
from the number of calls that the figures were increasing.” She said that
support and care provisions for victims and their families were “very patchy
really. In some areas it's like a postcode lottery, things just aren't
available when they're needed. The illness progresses very quickly; there
just isn't time to wait around. We have been asking the government for months
for a centralised care package, so that victims have consistent support.”


vCJD “cluster” in Leicestershire

Following the recent announcement of a “cluster” of five vCJD cases around
the Leicestershire village of Queniborough, a SEAC statement said it was
“unlikely to have occurred by chance,” but added that “this cannot be
completely ruled out”.

Like the majority of Human BSE victims, those who died in Queniborough
(population 2,297) in 1998 were young people, and included teenage mother
Stacey Robinson, 19. Van driver Glen Day, 35, and 24-year-old finance
administrator Pamela Bayless both succumbed to the disease in the same month.
Ms. Balyless's father said, “When Glen, Stacey and Pam all died within months
of each other, I spoke to Glen's dad and we discussed how strange it was that
it was all in Queniborough. It's such a rare disease.”

A 19-year-old man from the area died in June this year, and a 25-year-old
presently being nursed at home is another probable victim.

Dr. Robert Will, director of the government's CJD Surveillance Unit, said,
“Statistical evidence of a cluster might be of importance in identifying
further information on the causes of vCJD. But I am a bit cautious about it.
We have previously identified clusters which in the end turned out not to be
significant. That is the problem with rare phenomena—I am still not sure we
will find anything definite from this statistical anomaly.”

Unlike conventional CJD, which is most frequent in those over the age of 60
and is very rare in those below 50, vCJD has mainly affected young people. To
account for the high incidence in this age group, Dr. Will said that meat
processing methods in the 1980s might have led to contaminated meat ending up
on children's plates. “One possible explanation for the age distribution is
that young people tend to eat these products more than the adult population,”
he commented.

In an effort to boost profits, the beef industry introduced a process known
as “mechanically recovered meat.” This method employs high-pressure hoses to
obtain small amounts of tissue from animal carcasses. Despite the fact that
mechanically recovered meat could have contained the remnants of the spinal
cord, where BSE infectivity was known to be concentrated, the process was
only outlawed in 1995. The recovered meat scraps largely ended up in cheap
pies, sausages, burgers and ready-cooked meals. Such products were mainly
bought by those on low incomes, but could also be found in school meals and
infant foods.

However, not all scientists agree. Dr. Philip Monk, consultant in
communicable diseases for Leicestershire Health Authority, stated, “baby food
and school dinners” were not a factor in the Queniborough cluster. Initial
attention would be focused on the movement of cattle into the county. Local
abattoirs and meat processing plants will also be investigated to establish
if their products were sold regularly in local outlets. “We have been looking
into what patterns of slaughtering took place in this area of Leicestershire
and where meat from these slaughters entered the food chain,” Dr. Monk said.

Over 10,000 tonsils and appendixes removed in hospital operations carried out
in Leicestershire since 1985 may be tested for signs of CJD as part of a
national survey prompted by the Queniborough cluster. CJD is known to
incubate in these tissues in the early stages of the disease, however tests
on tonsils and appendixes carried out elsewhere in the UK have so far failed
to uncover signs of the disease.

There are indications that BSE also may have spread to other animals,
including sheep. After three flocks of sheep imported into the US from Europe
displayed signs of fatal brain disease, the sheep are to be destroyed. It is
not yet known if the animals had contracted a form of BSE, or a novel strain
of scrapie, which has existed in sheep for centuries.

The Food Standards Agency released a report Tuesday warning that present
safety measures were not tight enough to prevent “high risk” material from
sheep possibly containing a BSE agent from entering the human food chain.
According to the report, evidence that BSE has entered the national flock
“might emerge at any time in the next year or two.”

The number of eventual victims of Human BSE is still an unknown.
Epidemiologist Roy Anderson said that the total number of vCJD cases this
year “was likely to be greater than any previous year, so this epidemic is
just starting. It may be a small epidemic, and all of us hope it will be, but
this disease has such a long incubation period, where exposure was probably
in the late 1980s, that it's far too early to say whether it will be small,
medium or large.”

The Human BSE Foundation can be found at: http://www.hbsef.org

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