Friday January 21 12:20 PM ET

 NEW YORK, Jan 21 (Reuters Health) -- Despite concerns that fluoride
 consumption might weaken bones and increase the risk of fractures, a study
 from Britain indicates that drinking fluoridated water does not increase
 the rate of hip fractures.

 Fluoridation of water ``is not likely to have any important effect on the
 risk of hip fracture, and... concerns about this potential hazard should
 not be a reason for withholding the measure,'' report Dr. Sharon Hillier
 from University of Southampton, UK, and associates.

 In the study, ``one of the few investigations that have related fluoride
 ingestion to the risk of hip fracture in individuals,'' more than 500 men
 and women with hip fractures were compared with a similar number of others
 without hip fractures. According to results published in the January 22nd
 issue of The Lancet, the chance of fracturing a hip was the same for those
 who drank water containing fluoride in concentrations of about 1 part per
 million (ppm) as for those whose water contained less fluoride.

 Hip fracture risk was also equivalent between individuals living in areas
 with low fluoride concentration and those living where there was high
 fluoride concentration in the drinking water, the investigators note.

 Higher fluoride consumption increased the amount of fluoride found in the
 surfaces of bones, but not in their spongy interiors, the researchers
 indicate.

 Two factors did, however, influence the risk of fractures, Hillier and
 colleagues found. Thinner individuals -- those with lower body mass indexes
 -- were more likely to experience hip fractures, as were people who engaged
 in little physical activity.

 In a related editorial, Dr. Clifford Rosen from the Maine Center for
 Osteoporosis Research and Education in Bangor, Maine, writes that the study
 is ``extremely important because it joins only a handful of previous
 epidemiological investigations exploring the relation between fluoride
 ingestion to the risk of hip fractures.''

 ``These data,'' he adds, ``combined with those of (an earlier study),
 provide compelling evidence that lifelong exposure to fluoridated water
 does not increase the risk of hip fracture.''
 SOURCE: The Lancet 2000;355:265-269, 247-248.  >>



 Fluoride in water supply does not increase hip
 fractures

Friday January 21 12:20 PM ET

NEW YORK, Jan 21 (Reuters Health) -- Despite concerns that fluoride
consumption might weaken bones and increase the risk of fractures, a study
from Britain indicates that drinking fluoridated water does not increase
the rate of hip fractures.

Fluoridation of water ``is not likely to have any important effect on the
risk of hip fracture, and... concerns about this potential hazard should
not be a reason for withholding the measure,'' report Dr. Sharon Hillier
from University of Southampton, UK, and associates.

In the study, ``one of the few investigations that have related fluoride
ingestion to the risk of hip fracture in individuals,'' more than 500 men
and women with hip fractures were compared with a similar number of others
without hip fractures. According to results published in the January 22nd
issue of The Lancet, the chance of fracturing a hip was the same for those
who drank water containing fluoride in concentrations of about 1 part per
million (ppm) as for those whose water contained less fluoride.

Hip fracture risk was also equivalent between individuals living in areas
with low fluoride concentration and those living where there was high
fluoride concentration in the drinking water, the investigators note.

Higher fluoride consumption increased the amount of fluoride found in the
surfaces of bones, but not in their spongy interiors, the researchers
indicate.

Two factors did, however, influence the risk of fractures, Hillier and
colleagues found. Thinner individuals -- those with lower body mass indexes
-- were more likely to experience hip fractures, as were people who engaged
in little physical activity.

In a related editorial, Dr. Clifford Rosen from the Maine Center for
Osteoporosis Research and Education in Bangor, Maine, writes that the study
is ``extremely important because it joins only a handful of previous
epidemiological investigations exploring the relation between fluoride
ingestion to the risk of hip fractures.''

``These data,'' he adds, ``combined with those of (an earlier study),
provide compelling evidence that lifelong exposure to fluoridated water
does not increase the risk of hip fracture.''
SOURCE: The Lancet 2000;355:265-269, 247-248.

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