-Caveat Lector-

This study shows how the existence of PTSD might be measured physically.


Working memory in posttraumatic stress disorder--An event-related
potential study.
Galletly C, Clark CR, McFarlane AC, Weber DL
J Trauma Stress 2001 Apr 14:295-309

This study examined ERP topography during the updating and the
utilization of working memory in subjects with PTSD. Event-related
potentials of 18 participants with PTSD and 18 controls were recorded
from 32 scalp electrodes during an auditory target detection task
requiring the constant updating of target identity. Midline N2 and P3
abnormalities previously noted in PTSD during target detection were
replicated. Scalp topographic data revealed sustained reduction in
activity over the right hemisphere during working memory updating.
Executive processes were associated with brief but widespread right
hemisphere reductions during the P3, followed by sustained, bilateral
reduction frontally. This study identifies an abnormal pattern of
cortical network function during both the updating and use of working
memory in PTSD.

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