Reproduce it by going to System > Preferences > Keyboard. Add a new layout, and
attempt to change the default layout.
Yes this happens for all users.
Screenshot (grayed out, locked, radio button):
http://img396.imageshack.us/img396/1863/26sepfri1512nx9.png
By the way, sorry it got refiled under
Public bug reported:
Binary package hint: gnome-applets
It is impossible to change the default keyboard layout in System >
Preferences > Keyboard. The radio buttons are locked. There is no Unlock
button. If you run the program as root, it edits the keyboard settings
for root. I am on Ubuntu 8.04.