I do two things
1. Brick level (full) backup every single night - there is a LONG list
of reasons for this at my company - don't ask :-) - That's on tape LTO4
2. I also use CA (formerly XOSoft) WANSyncHA and do a live time
replication of my MASTER sever to my REPLICA server out at my DR site.
Sorry I am chiming in late on this but.
We use XOSoft's (now CA) WANSyncHA and I love it.
My replica/failover Exchange box is about 30 miles from my main office.
The TLS circuit between the two is 10MB. I have an Is Alive ping
between the two set for 10 minutes (allowing for reboots after