It looks like you are using MRS_200_UNI_MPRAGEised_stripped.nii for both the mov and the int. The int must be a full brain scan in registration with the slab. Also, it is better not to use --init-fsl (or any of the other --init-XXX flags)

On 1/4/2024 9:21 AM, Spapens, Jeltje (NP) wrote:
         External Email - Use Caution

Hi Douglas,

I hope you had some nice holidays and a happy beginning of 2024.

Thank you for your suggestion. I have added the intermediate picture and 
changed the MRI_vol2vol target volume from the original scan to the MRI/T1 
recon_all output. The latter one seemed to prevent the orientation shift. 
However, the registration still does not seem of very good quality. I have 
tried init-fsl, header and spm, but the first one gave the best results.

Do you have another advice for me?

bbregister --s MRS_200_recon_all --mov 
/Users/robspapens/Desktop/Thesis/Subjects/MRS_200/MRS_200_MT_tfl_stripped.nii 
--t2 --int 
/Users/robspapens/Desktop/Thesis/Subjects/MRS_200/presurf_MPRAGEise/MRS_200_UNI_MPRAGEised_stripped.nii
 --reg /Users/robspapens/Desktop/Thesis/Subjects/MRS_200/MRS_200_NM2mp2rage.dat 
 --init-fsl

mri_vol2vol --mov 
/Users/robspapens/Desktop/Thesis/Subjects/MRS_200/MRS_200_MT_tfl_stripped.nii 
--targ 
/Users/robspapens/Desktop/Thesis/Subjects/MRS_200/MRS_200_recon_all/mri/T1.mgz 
--o 
/Users/robspapens/Desktop/Thesis/Subjects/MRS_200/MRS_200_MT_tfl_regt1.nii.gz 
--reg /Users/robspapens/Desktop/Thesis/Subjects/MRS_200/MRS_200_NM2mp2rage.dat 
--cubic

Kind regards,

Jeltje Spapens


------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

Message: 15
Date: Mon, 1 Jan 2024 16:07:00 -0500
From: "Douglas N. Greve" <dgr...@mgh.harvard.edu  
<mailto:dgr...@mgh.harvard.edu>>
Subject: Re: [Freesurfer] FW: Boundary based registration
To:freesurfer@nmr.mgh.harvard.edu  <mailto:freesurfer@nmr.mgh.harvard.edu>
Message-ID: <e31f2342-e539-4ecc-b146-2b059dab1...@mgh.harvard.edu  
<mailto:e31f2342-e539-4ecc-b146-2b059dab1...@mgh.harvard.edu>>
Content-Type: text/plain; charset="utf-8"


Have you tried using the "intermediate" option (--int) in bbregister?
The intermediate volume should be a whole brain volume and it should
share a RAS space with the slab volume (eg, if they were acquired in the
same session; load both the slab and the intermediate in freeview to see
if they are aligned).
You can run bbregister with --help to get more info


On 12/13/2023 2:48 AM, Spapens, Jeltje (NP) wrote:
????????External Email - Use Caution

Hello Freesurfer developers,

I want to register an MRI slap to a full FoV UNI scan of the same
subject, but I get a false reorientation with my code (see attached
image). I have tried multiple input and tried the script on different
subjects.

I also changed som flags such as -init-header and --cubic, but all
seem to give the same results.

bbregister --s MRS_200_recon_all --mov
/Users/robspapens/Desktop/Thesis/Subjects/MRS_200/MRS_200_MT_tfl_stripped.mgz
--reg
/Users/robspapens/Desktop/Thesis/Subjects/MRS_200/MRS_200_NM2mp2rage.dat
--t2 --init-fsl

mri_vol2vol--mov
/Users/robspapens/Desktop/Thesis/Subjects/MRS_200/MRS_200_MT_tfl_stripped.mgz--targ
/Users/robspapens/Desktop/Thesis/Subjects/MRS_200/MRS_200_acpc_upsamp.nii
--o
/Users/robspapens/Desktop/Thesis/Subjects/MRS_200/MRS_200_MT_tfl_regt1.nii.gz
--reg
/Users/robspapens/Desktop/Thesis/Subjects/MRS_200/MRS_200_NM2mp2rage.dat
?trilin

I would appreciate to hear your thoughts on this problem.

Have a nice weekend and kind regards,

Jeltje Spapens



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