Is what about topological defects? There is not an error listed in the log file but it should have continued to run (this would not have anything to do with any topo defects). There could be a topo defect in the area outside of the skull that is labeled as cortex. In any event, you should fix this by fixing the brain mask (see online docs for editing a recon).

On 5/8/2020 2:08 PM, Zeng, Qi wrote:

        External Email - Use Caution

Hi Douglas and Bruce,

I reran the recon-all with freesurfer/*MailScanner has detected a possible fraud attempt from "7.0.0." claiming to be* 7.0.0. <http://7.0.0./> Now it generated more files (57) compared to normal run (81) in SUBJ/surf/ than freesurfer/6.0.0 (12) The script didn't exit with error but stopped running after about 10hrs. Attached the log file.
The script ends with "
writing registered surface to ../surf/rh.sphere.reg...
registration took 0.35 hours
#VMPC# mris_register VmPeak  3617640
FSRUNTIME@ mris_register  0.3463 hours 1 threads
@#@FSTIME  2020:05:06:22:35:52 mris_register N 6 e 1247.13 S 3.72 U 1239.39 P 99% M 3227664 F 0 R 2401997 W 0 c 128071 w 126 I 5584 O 0 L 19.04 19.01 18.97
@#@FSLOADPOST 2020:05:06:22:56:39 mris_register N 6 17.46 18.04 18.52"

Is it still about topological defects? Attached the white matter surface loading. It seems like there is no clear strip of the brain skull on the right top, is that so?

Thank you so much !
Best,
Qi



On Fri, May 8, 2020 at 2:06 PM Zeng, Qi <qi.z...@icahn.mssm.edu <mailto:qi.z...@icahn.mssm.edu>> wrote:

    Hi Douglas and Bruce,

    I reran the recon-all with freesurfer/*MailScanner has detected a
    possible fraud attempt from "7.0.0" claiming to be* *MailScanner
    warning: numerical links are often malicious:* 7.0.0.
    <http://7.0.0.> Now it generated more files (57) compared to
    normal run (81) in SUBJ/surf/ than freesurfer/6.0.0 (12)
    The script didn't exit with error but stopped running after about
    10hrs. Attached the log file.
    The script ends with "
    writing registered surface to ../surf/rh.sphere.reg...
    registration took 0.35 hours
    #VMPC# mris_register VmPeak  3617640
    FSRUNTIME@ mris_register  0.3463 hours 1 threads
    @#@FSTIME  2020:05:06:22:35:52 mris_register N 6 e 1247.13 S 3.72
    U 1239.39 P 99% M 3227664 F 0 R 2401997 W 0 c 128071 w 126 I 5584
    O 0 L 19.04 19.01 18.97
    @#@FSLOADPOST 2020:05:06:22:56:39 mris_register N 6 17.46 18.04 18.52"

    Is it still about topological defects? Attached the white matter
    surface loading. It seems like there is no clear strip of the
    brain skull on the right top, is that so?

    Thank you so much !
    Best,
    Qi


    On Wed, May 6, 2020 at 12:49 PM Douglas N. Greve
    <dgr...@mgh.harvard.edu <mailto:dgr...@mgh.harvard.edu>> wrote:

        Qi, in this context a "defect" is not just a place where the
        surface is inaccurate. It is a place where the surface is
        topologically incorrect, ie, a "handle" or a "hole" in the
        surface. Such defects are quite common and usually fixed by
        recon-all automatically. Sometimes the defects can be very
        large. This generally indicates a problem with the skull
        stripping or otherwise a failure to remove non-cortical
        regions. Your job is to find where this region is and fix it
        by fixing the skull strip or the wm.mgz file. Again, this is
        not going to be a small error in the surface -- it should be
        large.

        See
        
https://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/TopologicalDefect_freeview
        for more info

        On 5/6/2020 12:30 PM, Zeng, Qi wrote:

                External Email - Use Caution

        Hi Bruce,

        After examining the sagittal view of the parietal lobe, it is
        fine including the area.
        However, after examining the outputs in surf/, I noticed that
        after it generated lh.defects, it stopped processing
        lh.smoothwm and never got a chance to generate rh.defects.
        Compared to normal subjects that successfully finished, there
        is a clear mismatch between the inflated.nofix and the
        brainmask & wm.mgz. Attached below.

        Can you help confirm the fact of mismatch and let me know if
        there is any way to fix this?

        Thank you so much !
        Best,
        Qi

        On Wed, May 6, 2020 at 10:12 AM Bruce Fischl
        <fis...@nmr.mgh.harvard.edu
        <mailto:fis...@nmr.mgh.harvard.edu>> wrote:

            Hi Qi

            it is not obvious from that one image that something is
            wrong there. What
            does a saggital view look like with the cursor on that
            region? Also, can
            you send an image of the rh.inflated.nofix in 3D mode?
            Sometime XL
            defects are fixable automatically, which may be the case
            for your
            subjects with very large ventricles, but sometimes not

            cheers
            Bruce
            On Tue, 5 May 2020,
            Zeng, Qi wrote:

            >
            >         External Email - Use Caution
            >
            > Hi Douglas,
            >
            > Compared to the ones without error, the subject surface
            misses including
            > left parietal lobe. Is that correct? Attached the
            comparison.
            >
            > Thank you so much!
            > Best,
            > Qi
            >
            > On Tue, May 5, 2020 at 1:58 PM Douglas N. Greve
            <dgr...@mgh.harvard.edu <mailto:dgr...@mgh.harvard.edu>>
            > wrote:
            >       You should load that volume along with the
            orig.nofix hemisphere
            >       that is giving you problems and look for a large
            area that
            >       should not be within the surface
            >
            >       On 5/5/2020 1:23 PM, Zeng, Qi wrote:
            >
            >               External Email - Use Caution
            >
            >       Hi Douglas,
            >
            > The cerebrum is removed and with no skull attached.
            > However, compared to others that run normally,  it may have
            > problems with white matter segmentation and missing
            brainstem
            > (no clear). Attached the comparison below. Can you help
            figure
            > it out?
            >
            >
            >
            > Thank you so much!
            > Best,
            > Qi
            >
            > On Tue, May 5, 2020 at 11:36 AM Douglas N. Greve
            > <dgr...@mgh.harvard.edu
            <mailto:dgr...@mgh.harvard.edu>> wrote:
            >       You should look at the wm.mgz to see where the
            >       defect is. Probably cerebellum is still attached or
            >       maybe a big piece of skull.
            >
            >       On 5/4/2020 11:19 PM, Zeng, Qi wrote:
            >
            >               External Email - Use Caution
            >
            >       Hi,
            >
            > I've conducted longitudinal T1 recon-all. One
            > subject's last-scan ran into error in the first
            > independent recon all step: " recon-all -s SUBJ1
            > -SUBJ1.nii -all'.
            > Error: "CORRECTING DEFECT 0 (vertices=14101, convex
            > hull=2297, v0=1419) XL defect detected...". Log file
            > attached below.
            >
            > I've increased the memory usage limit as some
            > suggestions did, but no help. Also T1.nii looks
            > fine, same parameter setting as first scan, also
            > attached below. Subject first scan and all the other
            > subjects were finished without errors. Can you help
            > figure out what has caused it?
            >
            > Thank you so much!
            > Best,
            > Qi
            >
            > --
            >
            > Ph.D. candidate
            > Icahn School of Medicine at Mount Sinai
            >
            >
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        Icahn School of Medicine at Mount Sinai


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