Re: [Freesurfer] pial edit on atrophied temporal pole

2009-05-15 Thread Bruce Fischl
Hi Oliver, you might check with Mike Chee (ccd) who has some tools for editing of the mesh. Alternatively you could draw in some white matter (even if you can't see it) to get the pial surface a closer initialization. cheers, Bruce On Sat, 16 May 2009, Olivier Piguet wrote: Thanks for the in

Re: [Freesurfer] pial edit on atrophied temporal pole

2009-05-15 Thread Olivier Piguet
Thanks for the info. In severe cases of semantic dementia, you will see overall atrophy where the anterior temporal pole becomes almost non existent (combination of neuronal loss and white matter loss), probably also contributing to reduced white/grey differentiation. Is there a way to manu

Re: [Freesurfer] pial edit on atrophied temporal pole

2009-05-15 Thread Bruce Fischl
thanks Mike. Was it the same situation, where there is no nearby white matter? I guess I don't really understand the anatomy. Is there really a place where you have 10mm of gray matter with no underlying white matter? Or is it unmeylinated white matter that we just can't see? On Fri, 15 May 2

Re: [Freesurfer] pial edit on atrophied temporal pole

2009-05-15 Thread Michael Harms
As an aside, in a Alzheimer/ elderly cohort of ~250, we had 12 subjects that we had to exclude for what sounds like a very similar reason -- we just couldn't get the pial surface in the anterior temporal lobe to properly encapsulate the gray matter. -Mike H. On Fri, 2009-05-15 at 12:24 +1000, Ol

Re: [Freesurfer] pial edit on atrophied temporal pole

2009-05-14 Thread Olivier Piguet
That is correct. This is case of semantic dementia where left anterior temporal region is markedly atrophic. Olivier On 15/05/2009, at 9:15, Bruce Fischl wrote: so there's 10mm or so of gray matter with no underlying wm? I didn't think that was ever the case. What pathology is this in? And y

Re: [Freesurfer] pial edit on atrophied temporal pole

2009-05-14 Thread Bruce Fischl
so there's 10mm or so of gray matter with no underlying wm? I didn't think that was ever the case. What pathology is this in? And you're sure it's cortex, not amygdala? Jean: any thoughts? On Fri, 15 May 2009, Olivier Piguet wrote: Hi Bruce, In the coronal plane, slice 152 is the last slice

Re: [Freesurfer] pial edit on atrophied temporal pole

2009-05-14 Thread Olivier Piguet
Hi Bruce, In the coronal plane, slice 152 is the last slice where white matter is clearly visible. Then, slices 153-158, only grey matter is recognised but not all of it, and slices 159-164, grey matter is not recognised at all. I added control points on slice 151-153 in the hope that it w

Re: [Freesurfer] pial edit on atrophied temporal pole

2009-05-14 Thread Bruce Fischl
Hi Oliver, how far away is the nearest white matter? Bruce On Fri, 15 May 2009, Olivier Piguet wrote: Hi there, I haven't received a reply to my question below. Just to clarify, I ran autorecon1 and autorecon2 on this subject. When examining the surfaces in tkmedit, the left temporal pole

[Freesurfer] pial edit on atrophied temporal pole

2009-05-14 Thread Olivier Piguet
Hi there, I haven't received a reply to my question below. Just to clarify, I ran autorecon1 and autorecon2 on this subject. When examining the surfaces in tkmedit, the left temporal pole is not included in the pial surface. Is there a way to force freesurfer to recognise this as valid brai

[Freesurfer] pial edit on atrophied temporal pole

2009-05-12 Thread Olivier Piguet
Hi there, I've run autorecon2 on a subject who has significant unilateral atrophy in the anterior temporal region. In the last few slices anteriorly, the pial surface does not include what is clearly atrophied cortical tissue without underlying white matter. What is the method to correct f