Hi Woo-Suk
Just adding to Bruce's reply: area isn't a "technically more noisy and
usually thus less sensitive" as the reviewer suggests. Area isn't noisier
on its own right, and it's measured from the very same surfaces from which
thickness is measured. However, there is a much larger variability
Hi Woo-Suk
why not just do the surface analysis that they are requesting? I'm not
sure what you are asking, but certainly volume = surface area * thickness
in general, and so a volumetric effect can be driven by one or both of
surface area and thickness
cheers
Bruce
On
Sat, 27 Aug 2016, Wo
Dear FreeSurfer experts and developers
I am confronted with some technical question of a reviewer.
I am not sure about "volume = thickness-by-surface area" and the review's
opinion (attached below) about volume, surface area, and thickness was
correct.
Any comments from FreeSurfer's experts would