Re: [galaxy-user] analysing pooled data with FreeBayes

2013-07-24 Thread Erik Garrison
Hi, I wanted to identify that I've resolved this issue. The problem is that the tool must consider the likelihoods of all possible un-phased genotypes with N alleles and M copies across P pools. This becomes quite a big number when N becomes large and M is large, as it might in low-complexity lo

Re: [galaxy-user] copy number variation detcetion in Glaxay

2012-08-16 Thread Erik Garrison
Hi Mathew, To clarify, freebayes is not designed to detect CNVs. It can CNV information detected in another method to correctly genotype at sites with copy number variations. If you have exome data, there is conifer http:// conifer.sourceforge.net/