Mumbai launches Second line HIV drugs for testing New Delhi, Fri, 25 Jan
2008 NI Wire

Mumbai based J J hospital has announced to begin the process the second line
HIV drugs testing over 5 those persons who have developed the resistance
against the first line of drugs. These drugs were given to them from last
two years through Antiretroviral Therapy (ART) after identifying as HIV+
patients.

Unn health minister on World AIDS Day had announced to begin the testing
process of second line drugs soon in the country.


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J J hospital will the first to begin this process in the country while 10
others hospitals in India including Maulana Azad Medical College (Delhi),
PGI (Chandigarh) and ART centres in Kolkata, Manipur and Nagaland have also
been recommended to begin this process by April 2008.

"Eighteen patients have been screened and five of them were reviewed by the
panel," said Dr. B B Rewari, National Programme Officer (ART), National AIDS
Control Organisation, NACO in Mumbai. "They have been given the seven tablet
regime for the second line of drugs," he added.

Explaining the selecting criteria, Dr. Rewari said that those CD4 count had
fell below the baseline after a high or persistently remains less than 100
was eligible, besides those who developed opportunistic infections and whose
viral load count was 1,000 copies/ml.

The requirement of introducing this became necessary after observing the
NACO reports, which says that despite of very good adherence levels, nearly
3 to 5 percent of patients gain resistance against antiretroviral drugs
within nearly three years after beginning the treatment.

As much as 3,000 out of 1.2 lakh marked HIV+ patients are getting treatment
through ART and have gained resistance against first line of ART drugs, NACO
estimates.

NACO has decided to add 21 first line drug resistant patients every week in
Mumbai and Chennai to cover currently 3,000 patients.

"All of them will be put on second-line by December 2008," said Dr. Rewari.

The price of this second line drug therapy is very expensive against the
first line. It is nearly Rs.8,000 per months as against Rs. 8,000 per year
of first line therapy. "Bill and Melinda Gates foundation will provide these
drugs" informed Rewari.

Software tycoon, Bill Gates and his wife Melinda Gates had organised a
co-foundation for providing free drugs to HIV patients in 2000.

"We started work on the rollout more than two years ago with national
consultations on the need and feasibility of introducing second-line drugs
in view of the very high costs involved and building the capacities of
institutions and related laboratories on second-line drugs and tests," said
Dr Rewari.

NACO had began free Antiretroviral Therapy in 2004 from J J hospital and now
it has expanded its service to 137 ART centers in the 31 states
covering 1.2lakhs of HIV+ patients in which 20,000 are from
Maharashtra.




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