Dear Histonetters! Recently I cam across this new product offered by Polysciences, called HOPE Fixation( Hepes-glutamic acid buffer mediated Organic solvent Protection Effect). It claims that there is no retreival necessary for IHC and nor formalin either and that it makes even the hardest antibodies to work.So I was wondering if anyone out there has actually tried it out yet. Thank you. Sincerely, Igor Deyneko Infinity Pharmaceuticals Cambridge, MA 02139 _______________________________________________ Histonet mailing list Histonet@lists.utsouthwestern.edu http://lists.utsouthwestern.edu/mailman/listinfo/histonet