[Histonet] Re: Colon cancer

2008-11-23 Thread Robert Richmond
Probably 5 to 10% of colon cancers appear to be genetically inherited, a number that's likely to increase. Familial colonic polyposis is the best known of these inherited tumors, with almost all affected individuals getting colon cancer at an early age. Hereditary nonpolyposis cancer is more recent

[Histonet] Re: Colon Cancer

2008-11-22 Thread Shelly Coker
I work with many GI biopsies and occassionally we send off slides for testing for MSI (Microsattelite Instability).  This is a test for Hereditary Nonpolyposis Colorectal Cancer (HNPCC), also known as Lynch Sydrome.  The IHC tests for normal gene expression. You can "google" HNPCC or MSI and fin