Kelly Larson, HT(ASCP) at Pathology Services of West Michigan notes:
I am using Fix-All from Surgipath for bone marrow fixation. I empty the
syringe into the fixative as soon as it is handed to me (no messing around
with clots). I fix for 1-2 hours in Fix-All, then transfer to a screen
Now that we can no longer use mercury-containing fixatives, I don't
think that the various proprietary fixatives advocated for bone marrow
add anything to the morphology, and some of them can gum up processors
or interfere with immunohistochemistry.
Neutral buffered formalin requires time for
Ah, in a perfect world! (which would be down right boring, thanks)
Claire
Neutral buffered formalin requires time for fixation - clots need to
be cut up as soon as possible after they're received, and biopsy
specimens really ought to fix overnight before decalcification and
processing.
