This has been commented on several times by old fogey histotechs in the
past.
Any formalin variant takes some time to actually chemically alter (fix)
the tissue. Usually this is a minimum of 24 hours for a 3-4 mm thick
piece. In modern labs there is a focus on 24 hour or less turnaround
tim
Dear Histonetters:
I recently read the following in an article on Medscape:
"Underfixation of breast tissue may lead to false negative ER results and
false-positive HER2 results. In these situations, the tissue is actually fixed
in 100% ethanol, which is used to dehydrate the specimens after f
