We are looking at the cause of fragmentation on our bone marrow core biopsies.  
 We are reviewing fixative times and decalcification times.  Has anybody else 
experienced fragmentation problems?  If so how did you eliminate the problem?   
What other variables do I need to look at that might be the cause?   Thanks for 
the suggestions in advance.   We do use an AZF fixative and a gentle decal 
solution called Rapid-cal.

James Vickroy BS, HT(ASCP)

Surgical  and Autopsy Pathology Technical Supervisor
Memorial Medical Center
217-788-4046


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