Use a formic acid based decal solution and MAKE SURE the specimen does not
fix (formalin fixation) longer than 32hrs (false negatives result). Use 70%
ETOH to manage the fixation time (ie fix for 24 hours, decal for 4 hrs,
place in 70% ETOH until it gets put on the processor. Hold in 70% ETOH for
Hi Kendra-
Decal Stat from Statlab is HCl based, therefore is not appropriate for
subsequent IHC, ISH, or other molecular studies. There is lots of
peer-reviewed published data, if you need to supply rationale to your
pathologists. HCl is known to significantly reduce molecular assay
Hello all,
Recently, the Kappa/Lambda ISH has quit working on our decal specimens.
When we first validated ISH, we tested decal specimens that stained
appropriately. We use the DECAL Stat from StatLab. I did NOT do the initial
ISH validation back in 2019, but as far as I know, we have not changed
