Leonid,
I dont know what you hope to achieve with your survey. I cannot identify
a clear objective that can be reached by analysis of the results e.g.
your first question is a multi-part beast with cannot be answered with
just one YES/NO response.
Mark,
Like Leonid, you talk about error mes
Ken, Thanks for your comments, and I think your observation about how mechanistic (vs statistically rigorous) the analysts views are is really critical. Clearly Lewis (and at the risk of speaking for him, I think Nick perhaps) have strong views about this. Conversely, I heard many times (and am
Leonid,
I have never reported out as a final model a run that failed to converge or
failed the COV step. My guess is that individuals who frequently do probably
tend to be more mechanistic in their model building than I am and often push
the complexity of their models beyond what can be suppor
Mark,
"Useful" is the relative and subjective term. Error messages and
convergence information are useful to me (i.e., they make my search of
the final model more efficient), and I'd like to understand whether they
are useful to other people. I do not try to prove that the model
completed with
Leonid, Let me understand:You now have a theory that the way to determine whether the NONMEM error messages are useful (i.e., they tell you something about the model "goodness") is a poll. This, I think is a theory (and one well established in epistomolgy) of how to find an optimal solution - ap
Dear Susan:
We have no problem to run CWRES in xpose4 with NONMEM 6.2. But we did
not try the same code with NONMEM 6.1.
We made some changes to the control stream for nm 6.1 before running nm
6.2 as follows:
1) remove the "LAST block
2) change the $TABLE for FILE=cwtabx.deriv to take out all
