Hyewon,
The most obvious problem with your code is in $DES. You must use the
variable T not the variable TIME when referring to a time varying
hazard. TIME is the time on each data record. It does not change in
$DES. T is the time from the last data record upto the current data
record and cha
Hi Hyewon
My 2 cents of advice:
1. Note that you need to estimate the baseline hazard. You can then add
AUC as a covariate on the baseline hazard, or perhaps the Weibull shape
factor.
2. Because of my limited experience, I am not sure of the type of
survival distribution you are trying to model, bu
Dear NMuser
I am trying to analyze time to repeated event data using NONMEM.
The response were obtained till 24 hours after drug administration.
Inhibitory Emax model was implemented.
I am getting unreasonable parameter estimates which is far beyond what data
say.
If some body can point out what i
