>
> AN ERROR WAS FOUND IN THE CONTROL STATEMENTS.
>
> 274 $ESTIMATION: METHOD=COND NEEDED WITH LAPLACIAN OPTION.
>
>
> Mohd Rahimi Muda
>
>
>
> On Sun, Mar 24, 2024 at 7:09 AM Simbarashe Peter Zvada <
> simba.zv...@gmail.com> wrote:
>
>> Dear Mo
Dear Mohd,
Do you need METHOD=1 (COND) under $Estimation when you use LAPLACIAN?
I could be wrong, but just remove it and leave for defaults.
Thank you,
Simba
On Sat, Mar 23, 2024, 4:56 PM Mohd Rahimi wrote:
> Dear NONMEM user,
>
> I tried to run a VPC for M2 BQL method by using the co
Thanks Niurys for revisiting this.
It was discussed quite a lot before.
Using T in $DES, as Paolo suggested, is what I always do.
As far as your code / model file is concerned, I somehow like it as long as
you will be able to explain in simpler terms to non-pharmacometricians and
Physicians what t
Hi Sumeet and Sebastian,
Following Mannie's suggestion, sometimes starting with the file works, may
be not in all cases:
$TABLE FILE=mytab1.csv FORMAT=, ID TIME CMT ... IPRED NOPRINT ONEHEADER
Thanks,
Simba
On Thu, Mar 14, 2019 at 4:21 PM Singla, Sumeet K
wrote:
> Emmanuel,
>
>
>
> It didn
> Your paper is very useful. I actually used the same model to fit. But, it
> (even without IOV) was over-parametrized . You had 14 time points, I only
> have 6 time points (including time 0).
>
> Bo
>
>
>
> On Wed, May 23, 2012 at 11:14 AM, Simbarashe Peter Zvada <
>
Dear Lata
If I understand correctly that you are not referring to single dose
per occasion/period, compound PK can be affected by its physiological
effects.
For example, a compound can induce its own clearance / elimination
(autoinduction) after a couple of consecutive doses.
This is particularly
